Acute hypobaric hypoxia (AHH) exposure causes altitude mountain sickness (AMS) and life-
threatening high altitude cerebral edema (HACE). Despite decades of research, the role of …

Background Exposure to acute hypobaric hypoxia (AHH) during ascent to high altitudes (>
3500 m) is one of the main causes of acute mountain sickness (AMS) and high-altitude …

Acute mountain sickness (AMS) and high-altitude cerebral edema share common clinical
characteristics, suggesting cerebral swelling may be an important factor in the …

High altitude cerebral edema (HACE) is a life-threatening illness that develops during the
rapid ascent to high altitudes, but its underlying mechanisms remain unclear. Growing …

High-altitude environments present extreme conditions characterized by low barometric
pressure and oxygen deficiency, which can disrupt brain functioning and cause edema …

Traditionally, scientists and clinicians have explored peripheral physiological responses to
acute hypoxia to explain the pathophysiological processes that lead to acute mountain …

Background High-altitude cerebral edema (HACE) is the severe type of acute mountain
sickness (AMS) and life threatening. A subclinical inflammation has been speculated, but the …

Acute mountain sickness (AMS) develops within a few hours after arrival at high altitude and
includes headache, anorexia, nausea, vomiting, and malaise. This afflicts 15–25% of the …

Objective: Hypoxic exposure in healthy subjects can induce acute mountain sickness
including headache, lethargy, cerebral dysfunction, and substantial cerebral structural …

High-altitude hypoxia (HH) causes a spectrum of pathophysiological effects, including
headaches, gliovascular dysfunction, and cognitive slowing. Previous studies have shown …