Phytochemical antioxidants modulate mammalian cellular epigenome: implications in health and disease
In living systems, the mechanisms of inheritance involving gene expression are operated by
(i) the traditional model of genetics where the deoxyribonucleic acid (DNA) transcription and …
(i) the traditional model of genetics where the deoxyribonucleic acid (DNA) transcription and …
Dietary antioxidants remodel DNA methylation patterns in chronic disease
M Beetch, S Harandi‐Zadeh, K Shen… - British journal of …, 2020 - Wiley Online Library
Chronic diseases account for over 60% of all deaths worldwide according to the World
Health Organization reports. Majority of cases are triggered by environmental exposures that …
Health Organization reports. Majority of cases are triggered by environmental exposures that …
The role of dietary phenolic compounds in epigenetic modulation involved in inflammatory processes
M Číž, A Dvořáková, V Skočková, L Kubala - Antioxidants, 2020 - mdpi.com
A better understanding of the interactions between dietary phenolic compounds and the
epigenetics of inflammation may impact pathological conditions and their treatment …
epigenetics of inflammation may impact pathological conditions and their treatment …
Health-promoting role of dietary bioactive compounds through epigenetic modulations: a novel prophylactic and therapeutic approach
The epigenome is an overall epigenetic state of an organism, which is as important as that of
the genome for normal development and functioning of an individual. Epigenetics involves …
the genome for normal development and functioning of an individual. Epigenetics involves …
Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges
The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …
derived natural bioactive compounds (phytochemicals) have acquired an important role in …
Redox signaling, mitochondrial metabolism, epigenetics and redox active phytochemicals
Biological redox signaling plays an important role in many diseases. Redox signaling
involves reductive and oxidative mechanisms. Oxidative stress occurs when reductive …
involves reductive and oxidative mechanisms. Oxidative stress occurs when reductive …
Dietary phytochemicals and cancer chemoprevention: a perspective on oxidative stress, inflammation, and epigenetics
Oxidative stress occurs when cellular reactive oxygen species levels exceed the self-
antioxidant capacity of the body. Oxidative stress induces many pathological changes …
antioxidant capacity of the body. Oxidative stress induces many pathological changes …
Nutriepigenomics in environmental-associated oxidative stress
K Rubio, EY Hernández-Cruz, DG Rogel-Ayala… - Antioxidants, 2023 - mdpi.com
Complex molecular mechanisms define our responses to environmental stimuli. Beyond the
DNA sequence itself, epigenetic machinery orchestrates changes in gene expression …
DNA sequence itself, epigenetic machinery orchestrates changes in gene expression …
The redox basis of epigenetic modifications: from mechanisms to functional consequences
Epigenetic modifications represent mechanisms by which cells may effectively translate
multiple signaling inputs into phenotypic outputs. Recent research is revealing that redox …
multiple signaling inputs into phenotypic outputs. Recent research is revealing that redox …
A perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomics
Oxidative stress is caused by an imbalance of reactive oxygen species (ROS)/reactive
nitrogen species (RNS) and the antioxidative stress defense systems in cells. ROS/RNS or …
nitrogen species (RNS) and the antioxidative stress defense systems in cells. ROS/RNS or …