Among the different behavioral criteria used to discriminate substance dependence (or drug
addiction) from other non-disordered forms of drug use, drug intake escalation presents a …

Fish models and behaviors are increasingly used in the biomedical sciences; however, fish
have long been the subject of ecological, physiological and toxicological studies. Using …

Behavioral neuroscience is an interdisciplinary field aimed at understanding the
neurobiology of behavior. Numerous investigators turn to animals to model and understand …

Zebrafish genetics is developing at a rapid pace, and this opens up new approaches to
understanding genetic control. This short review discusses recent results obtained in …

Abstract Changes in the expression of the dopamine transporter (DAT), or the sensitivity of
dopamine receptors, are associated with aging and substance abuse and may underlie …

Zebrafish, a vertebrate model organism amenable to high throughput screening, is an
attractive system to model and study the mechanisms underlying human diseases …

The zebrafish has been an excellent model organism of developmental biology and
genetics. Studying its behavior will add to the already strong knowledge of its biology and …

Addiction is a complex maladaptive behavior involving alterations in several
neurotransmitter networks. In mammals, psychostimulants trigger elevated extracellular …

The use of adult zebrafish (Danio rerio) in neurobehavioral research is rapidly expanding.
The present large-scale study applied the newest video-tracking and data-mining …

It is increasingly recognized that studying drug taking in laboratory animals does not equate
to studying genuine addiction, characterized by loss of control over drug use. This has …