Gamma hydroxy butyrate abuse and dependency

A Gonzalez, DJ Nutt - Journal of Psychopharmacology, 2005 - journals.sagepub.com
The recreational use of gamma hydroxy butyrate (GHB) has gained popularity over the last
decade. GHB was initially sold as a safe bodybuilding and fat burning compound. It is now …

Sites of action of gamma-hydroxybutyrate (GHB)–a neuroactive drug with abuse potential

G Tunnicliff - Journal of Toxicology: Clinical Toxicology, 1997 - Taylor & Francis
Objective: This review highlights the biochemistry, pharmacology, and toxicology of the
naturally-occurring fatty acid derivative, gamma-hydroxy-butyrate (GHB). GHB is derived …

A case of gamma-hydroxybutyric acid withdrawal syndrome during alcohol addiction treatment: utility of diazepam administration

G Addolorato, F Caputo, E Capristo… - Clinical …, 1999 - journals.lww.com
Gamma-hydroxybutyric acid (GHB) is an emerging drug for alcoholism therapy. We present
a case of GHB withdrawal syndrome secondary to GHB addiction during alcoholism …

Characteristics of analytically confirmed gamma-hydroxybutyrate (GHB) positive patients in the emergency department: presentation, poly-drug use, disposition and …

P Stockham, E Partridge, S Alfred, L Boyle… - Clinical …, 2023 - Taylor & Francis
Background Gamma-hydroxybutyrate is a potent central nervous system depressant with a
narrow recreational dose window and analytical detection time. We describe data relating to …

[PDF][PDF] Gamma butyrolactone (GBL) withdrawal syndromes

MC Catalano, JM Glass, G Catalano, SL Burrows… - …, 2001 - researchgate.net
Abuse of gamma hydroxybutyrate (GHB) and gamma butyrolactone (GBL) has been
increasing rapidly recently, and consultation-liaison psychiatrists are being called to …

[PDF][PDF] Gamma-hydroxybutyric acid, gamma-butyrolactone, and 1, 4-butanediol addiction: a serious health threat

R Beck, S Mimica Matanović, L Zibar - Arhiv za higijenu rada i …, 2019 - hrcak.srce.hr
Gamma-hydroxybutyric acid (GHB) and its precursors gamma-butyrolactone (GBL) and 1, 4-
butanediol (1, 4-BD) pose a serious threat to the health of (ab) users, and the aim of this …

Safety and tolerability of gamma-hydroxybutyric acid in the treatment of alcohol-dependent patients

F Beghè, MT Carpanini - Alcohol, 2000 - Elsevier
Gamma-hydroxybutyric acid (GHB) has been in clinical use in Italy since 1991 for treatment
of alcohol dependence. Results of phase III and phase IV studies have shown that the drug …

[HTML][HTML] Temporal differences in gamma-hydroxybutyrate overdoses involving injecting drug users versus recreational drug users in Helsinki: a retrospective study

JJ Boyd, MJ Kuisma, TT Randell - Scandinavian Journal of Trauma …, 2012 - Springer
Background Gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL) have been
profiled as' party drugs' used mainly at dance parties and in nightclubs on weekend nights …

[HTML][HTML] Gamma hydroxybutyric acid (GHB) for the treatment of alcohol dependence: a review

F Caputo, T Vignoli, I Maremmani, M Bernardi… - International Journal of …, 2009 - mdpi.com
Gamma-hydroxybutyric acid (GHB) is a short-chain fatty acid structurally similar to the
inhibitory neurotransmitter γ-aminobutyric acid. Clinical trials have demonstrated that 50 …

[PDF][PDF] GHB: an important pharmacologic and clinical update

MS Okun, LA Boothby, RB Bartfield, PL Doering - J Pharm Pharm Sci, 2001 - academia.edu
Gamma-hydroxybutyrate (GHB) intoxication is a significant cause of morbidity and mortality
in patients taking the drug for recreational purposes. Due to the recent increase in …