MyoD is a member of the basic‐helix‐loop‐helix (bHLH) transcription factor family, which
regulates muscle determination and differentiation in vertebrates. While it is now well …

Transgenic analyses have defined two transcriptional enhancers that regulate MyoD
expression in mammals, the core enhancer and distal regulatory region; these enhancers …

Transgenic analyses have defined two MyoD enhancers in mammals, the core enhancer
and distal regulatory region (DRR); these enhancers exhibit complementary activities and …

Transgenic mice carrying the bacterial lacZ reporter gene under the control of the regulatory
elements of the human myoD gene have been produced. The developmental expression of …

MyoD belongs to a small family of basic helix-loop-helix transcription factors implicated in
skeletal muscle lineage determination and differentiation. Previously, we identified a …

Skeletal muscle lineage determination is regulated by the myogenic regulatory genes, MyoD
and Myf-5. Previously, we identified a 258 bp core enhancer element 20 kb 5′ of the MyoD …

To analyze the transcriptional regulatory mechanisms of the myoD gene, we generated
transgenic mice bearing a lacZ gene driven by a 6-kb 5′-flanking sequence of the mouse …

MYOD is a master regulator of the skeletal myogenic program. But what regulates
expression of Myod? More than 20 years ago, studies established that Myod expression is …

The MyoD family of basic helix-loop-helix (bHLH) transcription factors has the remarkable
ability to induce myogenesis in vitro and in vivo. This myogenic specificity has been mapped …

The MyoD family of transcription factors are expressed in the skeletal muscles of vertebrate
and invertebrate embryos and have dominant regulatory activities that indicate their …