DNA methylation biomarkers of stool and blood for early detection of colon cancer

L Hong, N Ahuja - Genetic testing and molecular biomarkers, 2013 - liebertpub.com
Detection of colorectal cancer at an early stage may significantly decrease mortality from the
disease. The current screening test of colonoscopy is of high efficacy, but its acceptance in …

[HTML][HTML] Serum-based DNA methylation biomarkers in colorectal cancer: potential for screening and early detection

T Summers, RC Langan, A Nissan… - Journal of …, 2013 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cause of cancer-related death in the
United States. Early identification and treatment of pre-cancerous colorectal lesions, or node …

[HTML][HTML] DNA methylation markers detected in blood, stool, urine, and tissue in colorectal cancer: a systematic review of paired samples

EA Laugsand, SS Brenne, F Skorpen - International Journal of Colorectal …, 2021 - Springer
Purpose Methylated cell-free DNA in liquid biopsies are promising non-invasive biomarkers
for colorectal cancer (CRC). Optimal markers would have high sensitivity and specificity for …

[HTML][HTML] Novel DNA methylation biomarkers in stool and blood for early detection of colorectal cancer and precancerous lesions

Y Shen, D Wang, T Yuan, H Fang, C Zhu, J Qin, X Xu… - Clinical …, 2023 - Springer
Background Early detection and prevention of precancerous lesions can significantly reduce
the morbidity and mortality of colorectal cancer (CRC). Here, we developed new candidate …

Noninvasive DNA methylation biomarkers in colorectal cancer: a systematic review

M Xue, SC Lai, ZP Xu, LJ Wang - Journal of digestive diseases, 2015 - Wiley Online Library
Objective To summarize the current evidence on the biomarkers associated with DNA
methylation in the screening and diagnosis of colorectal cancer (CRC). Methods A literature …

A systematic review and quantitative assessment of methylation biomarkers in fecal DNA and colorectal cancer and its precursor, colorectal adenoma

R Liu, X Su, Y Long, D Zhou, X Zhang, Z Ye… - … Research/Reviews in …, 2019 - Elsevier
Colorectal cancer (CRC) arises from accumulated genetic and epigenetic alterations, which
provide the possibility to identify tumor-specific biomarkers by analyzing fecal DNA …

DNA methylation in colorectal cancer—impact on screening and therapy monitoring modalities?

M Zitt, M Zitt, HM Müller - Disease markers, 2007 - Wiley Online Library
Colorectal cancer (CRC) is a common malignancy. It arises from benign neoplasms and
evolves into adenocarcinomas through a stepwise histological progression sequence …

DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicine

N Fatemi, S Tierling, HA Es, M Varkiani… - … journal of cancer, 2022 - Wiley Online Library
Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …

[HTML][HTML] Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: A review of literature

M Galanopoulos, N Tsoukalas… - World journal of …, 2017 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most prevalent malignancies in the world. CRC-
associated morbidity and mortality is continuously increasing, in part due to a lack of early …

DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer

FJ Carmona, D Azuara, A Berenguer-Llergo… - Cancer prevention …, 2013 - AACR
DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer (CRC) and
precursor lesions have been extensively studied. Different panels have been reported …