Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

MJ Aryee, AE Jaffe, H Corrada-Bravo… - …, 2014 - academic.oup.com
Abstract Motivation: The recently released Infinium HumanMethylation450 array (the
'450k'array) provides a high-throughput assay to quantify DNA methylation (DNAm) at∼ 450 …

RnBeads 2.0: comprehensive analysis of DNA methylation data

F Müller, M Scherer, Y Assenov, P Lutsik, J Walter… - Genome biology, 2019 - Springer
DNA methylation is a widely investigated epigenetic mark with important roles in
development and disease. High-throughput assays enable genome-scale DNA methylation …

[HTML][HTML] A cross-package Bioconductor workflow for analysing methylation array data

J Maksimovic, B Phipson, A Oshlack - F1000Research, 2016 - ncbi.nlm.nih.gov
Methylation in the human genome is known to be associated with development and disease.
The Illumina Infinium methylation arrays are by far the most common way to interrogate …

DNA methylation data analysis and its application to cancer research

X Ma, YW Wang, MQ Zhang, AF Gazdar - Epigenomics, 2013 - Taylor & Francis
With the rapid development of genome-wide high-throughput technologies, including
expression arrays, SNP arrays and next-generation sequencing platforms, enormous …

missMethyl: an R package for analyzing data from Illumina's HumanMethylation450 platform

B Phipson, J Maksimovic, A Oshlack - Bioinformatics, 2015 - academic.oup.com
DNA methylation is one of the most commonly studied epigenetic modifications due to its
role in both disease and development. The Illumina HumanMethylation450 BeadChip is a …

Using high-density DNA methylation arrays to profile copy number alterations

A Feber, P Guilhamon, M Lechner, T Fenton… - Genome biology, 2014 - Springer
The integration of genomic and epigenomic data is an increasingly popular approach for
studying the complex mechanisms driving cancer development. We have developed a …

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

EM Price, AM Cotton, LL Lam, P Farré, E Emberly… - Epigenetics & …, 2013 - Springer
Background Measurement of genome-wide DNA methylation (DNAm) has become an
important avenue for investigating potential physiologically-relevant epigenetic changes …

IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data

D Wang, L Yan, Q Hu, LE Sucheston, MJ Higgins… - …, 2012 - academic.oup.com
The Illumina Infinium HumanMethylation450 BeadChip is a newly designed high-density
microarray for quantifying the methylation level of over 450 000 CpG sites within human …

ChAMP: 450k chip analysis methylation pipeline

TJ Morris, LM Butcher, A Feber, AE Teschendorff… - …, 2014 - academic.oup.com
Abstract The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-
throughput DNA methylation analysis. Several methods for normalization and processing of …

Bigmelon: tools for analysing large DNA methylation datasets

TJ Gorrie-Stone, MC Smart, A Saffari, K Malki… - …, 2019 - academic.oup.com
Motivation The datasets generated by DNA methylation analyses are getting bigger. With the
release of the HumanMethylationEPIC micro-array and datasets containing thousands of …