The Council of Europe should not reaffirm the ban on germline genome editing in humans

P Sykora, A Caplan - EMBO reports, 2017 - embopress.org
Europe is resolutely on its way to reaffirming a 20-year-old policy banning all inheritable
interventions involving the human genome. This approach, which was well justified two …

The Council of Europe and the prohibition on human germline genome editing

F Baylis, L Ikemoto - EMBO reports, 2017 - embopress.org
According to Sykora and Caplan, the CRISPR/Cas9 genome “editing” system is more
efficient and precise than previous technologies for making intentional modifications to the …

Chapter 11 Germline Gene Therapy in the Era of Precise Genome Editing: How Far Should We Go?

P Sýkora - The Ethics of Reproductive Genetics: Between Utility …, 2018 - Springer
Since the creation of the first transgenic animals four decades ago, a wide ethical consensus
has been reached that in contrast to a somatic gene therapy, germline gene interventions in …

Risks and benefits of human germline genome editing: An ethical analysis

G Rubeis, F Steger - asian bioethics review, 2018 - Springer
With the arrival of new methods of genome editing, especially CRISPR/Cas 9, new
perspectives on germline interventions have arisen. Supporters of germ line genome editing …

[HTML][HTML] Human germline interventions–think first

E Hildt - Frontiers in genetics, 2016 - frontiersin.org
Recent studies using gene editing tools such as CRISPR/Cas9 have shown an enormously
broad spectrum of possible future applications. This genetic engineering technique allows …

[PDF][PDF] Responsible innovation in human germline gene editing. Background document to the recommendations of ESHG and ESHRE

G De Wert, B Heindryckx, G Pennings… - Human …, 2018 - academic.oup.com
Technological developments in gene editing raise high expectations for clinical applications,
including editing of the germline. The European Society of Human Reproduction and …

Ethics and germline gene editing

J Sugarman - EMBO reports, 2015 - embopress.org
The current kerfuffle around the use of CRISPR/Cas9 and other gene editing technologies in
human germline research is the latest in a series of related controversies at the intersection …

One small edit for humans, one giant edit for humankind? Points and questions to consider for a responsible way forward for gene editing in humans

HC Howard, CG van El, F Forzano… - European Journal of …, 2018 - nature.com
Gene editing, which allows for specific location (s) in the genome to be targeted and altered
by deleting, adding or substituting nucleotides, is currently the subject of important academic …

[图书][B] Human Germline Modification and the Right to Science: A Comparative Study of National Laws and Policies

A Boggio, CPR Romano, J Almqvist - 2020 - books.google.com
The advent of the CRISPR/Cas9 class of genome editing tools is transforming not just
science and medicine, but also law. When the genome of germline cells is modified, the …

Playing it safe? Precaution, risk, and responsibility in human genome editing

S Chan - Perspectives in Biology and Medicine, 2020 - muse.jhu.edu
Human germline genetic modification has long been a controversial topic. Until recently it
remained largely a hypothetical debate: whether one accepted or opposed the idea in …