Epigenetic modifications are a mechanism conveying environmental information to
subsequent generations via parental germ lines. Research on epigenetic responses to …

Exceptionally long-lived species, including many bats, rarely show overt signs of aging,
making it difficult to determine why species differ in lifespan. Here, we use DNA methylation …

DNA methylation is an essential epigenetic mark whose role in gene regulation and its
dependency on genomic sequence and environment are not fully understood. In this study …

DNA methylation-based biomarkers of aging have been developed for many mammals but
not yet for the vervet monkey (Chlorocebus sabaeus), which is a valuable non-human …

The age, sex, and sexual maturity of individual animals are key parameters in assessing
wild populations and informing conservation management strategies. These parameters …

Epigenetic mechanisms convey environmental information through generations and can
regulate gene expression. Epigenetic studies in wild mammals are rare, but enable …

DNA is methylated at the dinucleotide CpG in genomes of a wide range of plants and
animals. Among animals, variable patterns of genomic CpG methylation have been …

DNA methylation is an epigenetic modification that plays a crucial role in various regulatory
processes, including gene expression regulation, transposable element repression, and …

Background The discovery of gene body methylation, which refers to DNA methylation within
gene coding region, suggests an as yet unknown role of DNA methylation at actively …

It is known that aged organisms have modified epigenomes. Epigenetic modifications, such
as changes in global and locus-specific DNA methylation, and histone modifications are …