Abstract S‐Adenosylmethionine (SAMe), the principal biological methyl donor, is
synthesized from methionine and ATP in a reaction catalyzed by methionine …

S-adenosylmethionine (AdoMet, also known as SAM and SAMe) is the principal biological
methyl donor synthesized in all mammalian cells but most abundantly in the liver …

Two genes (MAT1A and MAT2A) encode for the essential enzyme methionine
adenosyltransferase (MAT), which catalyzes the biosynthesis of S-adenosylmethionine …

Liver–specific and non-liver–specific methionine adenosyltransferase (MAT) are products of
two genes, MAT1A and MAT2A, respectively, that catalyze the formation of S …

Methionine metabolism starts with the formation of S-adenosylmethionine (AdoMet), the
most important biological methyl donor. This reaction is catalyzed by methionine …

Alterations of methionine cycle in steatohepatitis, cirrhosis, and hepatocellular carcinoma
induce MAT1A decrease and MAT2A increase expressions with the consequent decrease of …

SAMe (S-adenosylmethionine) is the main methyl donor group in the cell. MAT (methionine
adenosyltransferase) is the unique enzyme responsible for the synthesis of SAMe from …

Methionine adenosyltransferase (MAT), an essential enzyme that catalyzes the formation of
S-adenosylmethionine (SAM), is encoded by two genes, MAT1A (liver-specific) and MAT2A …

Methionine adenosyltransferases (MATs) are essential enzymes for life as they produce S-
adenosylmethionine (SAMe), the biological methyl donor required for a plethora of reactions …

Liver-specific and nonliver-specific methionine adenosyltransferases (MATs) are products of
two genes, MAT1A and MAT2A, respectively, that catalyze the formation of S …