[HTML][HTML] Epigenetic reprogramming in mouse primordial germ cells
Genome-wide epigenetic reprogramming in mammalian germ cells, zygote and early
embryos, plays a crucial role in regulating genome functions at critical stages of …
embryos, plays a crucial role in regulating genome functions at critical stages of …
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification
F von Meyenn, RV Berrens, S Andrews, F Santos… - Developmental cell, 2016 - cell.com
Primordial germ cell (PGC) development is characterized by global epigenetic remodeling,
which resets genomic potential and establishes an epigenetic ground state. Here we …
which resets genomic potential and establishes an epigenetic ground state. Here we …
[HTML][HTML] Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice
Y Seki, K Hayashi, K Itoh, M Mizugaki, M Saitou… - Developmental …, 2005 - Elsevier
Induction of mouse germ cells occurs from the proximal epiblast at around embryonic day
(E) 7.0. These germ cells then migrate to, and enter the gonads at about E10. 5 after which …
(E) 7.0. These germ cells then migrate to, and enter the gonads at about E10. 5 after which …
Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells
M Saitou, S Kagiwada, K Kurimoto - Development, 2012 - journals.biologists.com
Epigenetic modifications are crucial for the identity and stability of cells, and, when aberrant,
can lead to disease. During mouse development, the genome-wide epigenetic states of pre …
can lead to disease. During mouse development, the genome-wide epigenetic states of pre …
Global profiling of DNA methylation erasure in mouse primordial germ cells
S Guibert, T Forné, M Weber - Genome research, 2012 - genome.cshlp.org
Epigenetic reprogramming, characterized by loss of cytosine methylation and histone
modifications, occurs during mammalian development in primordial germ cells (PGCs), yet …
modifications, occurs during mammalian development in primordial germ cells (PGCs), yet …
Epigenetic Reprogramming in Mice and Humans: From Fertilization to Primordial Germ Cell Development
A Singh, DA Rappolee, DM Ruden - Cells, 2023 - mdpi.com
In this review, advances in the understanding of epigenetic reprogramming from fertilization
to the development of primordial germline cells in a mouse and human embryo are …
to the development of primordial germline cells in a mouse and human embryo are …
A replication-dependent passive mechanism modulates DNA demethylation in mouse primordial germ cells
R Ohno, M Nakayama, C Naruse, N Okashita… - …, 2013 - journals.biologists.com
Germline cells reprogramme extensive epigenetic modifications to ensure the cellular
totipotency of subsequent generations and to prevent the accumulation of epimutations …
totipotency of subsequent generations and to prevent the accumulation of epimutations …
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells
Genome-wide DNA methylation reprogramming occurs in mouse primordial germ cells
(PGCs) and preimplantation embryos, but the precise dynamics and biological outcomes are …
(PGCs) and preimplantation embryos, but the precise dynamics and biological outcomes are …
Primordial germ-cell development and epigenetic reprogramming in mammals
Primordial germ cells (PGCs) are the embryonic precursors of the gametes and represent
the founder cells of the germline. Specification of PGCs is a critical divergent point during …
the founder cells of the germline. Specification of PGCs is a critical divergent point during …
Developmental potential of mouse primordial germ cells
Y Kato, WM Rideout, K Hilton, SC Barton… - …, 1999 - journals.biologists.com
There are distinctive and characteristic genomic modifications in primordial germ cells that
distinguish the germ cell lineage from somatic cells. These modifications include, genome …
distinguish the germ cell lineage from somatic cells. These modifications include, genome …