De novo DNA methylation (DNAme) during mouse oogenesis occurs within transcribed
regions enriched for H3K36me3. As many oocyte transcripts originate in long terminal …

Background Previously, a role was demonstrated for transcription in the acquisition of DNA
methylation at imprinted control regions in oocytes. Definition of the oocyte DNA methylome …

DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly
accepted that the paternal genome is actively depleted of 5-methylcytosine at fertilization …

DNA methylation is an epigenetic modification that plays a crucial role in normal mammalian
development, retrotransposon silencing, and cellular reprogramming. Although methylation …

DNA methylation plays important roles during development. However, the DNA methylation
reprogramming of functional elements has not been fully investigated during mammalian …

DNA methylation is globally reprogrammed during mammalian preimplantation
development, which is critical for normal development. Recent reduced representation …

DNA methylation is a tightly regulated epigenetic mark associated with transcriptional
repression. Next-generation sequencing of purified methylated DNA obtained from early …

Identifying loci with parental differences in DNA methylation is key to unraveling parent-of-
origin phenotypes. By conducting a MeDIP-Seq screen in maternal-methylation free …

Thousands of regions in gametes have opposing methylation profiles that are largely
resolved during the post-fertilization epigenetic reprogramming. However some specific …

Elucidating how and to what extent CpG islands (CGIs) are methylated in germ cells is
essential to understand genomic imprinting and epigenetic reprogramming,,. Here we …