Background Stool-based molecular tests hold large potential for improving colorectal cancer
screening. Here, we investigated the analytical sensitivity of a DNA methylation assay on …

Colorectal cancer (CRC) is a significant global health challenge, ranking among the leading
causes of cancer-related mortality worldwide. Despite efforts in prevention and early …

Background: Assay of methylated DNA markers in stool is a promising approach for
colorectal cancer (CRC) screening. A method to capture hypermethylated CpG islands from …

Aim There is not sufficient evidence about whether stool DNA methylation tests allow
prioritizing patients to colonoscopy. Due to the COVID‐19 pandemic, there will be a wait‐list …

Detection of colorectal cancer at an early stage may significantly decrease mortality from the
disease. The current screening test of colonoscopy is of high efficacy, but its acceptance in …

Colorectal cancer (CRC) arises from accumulated genetic and epigenetic alterations, which
provide the possibility to identify tumor-specific biomarkers by analyzing fecal DNA …

Background Because of poor compliance or low sensitivity, existing diagnostic approaches
are unable to provide an efficient diagnosis of patients with gastric and colorectal cancer …

Background Previous studies showed that the assessment of promoter hypermethylation of
a limited number of genes in tumor biopsies may identify the majority of colorectal tumors …

Colorectal cancer (CRC) is fourth most common cancer in men and third in women
worldwide. Developing a diagnostic panel of sensitive and specific biomarkers for the early …

Purpose Methylated cell-free DNA in liquid biopsies are promising non-invasive biomarkers
for colorectal cancer (CRC). Optimal markers would have high sensitivity and specificity for …