Background Many drugs are used off-label or unlicensed in neonates. This does not mean
they are used without evidence or knowledge. We aimed to apply and evaluate the Grading …

Sedation is currently administered to neonates experiencing pain and stress during
intensive care for medical diseases, as well as postoperatively. Drugs commonly used for …

In a randomized, double-blind, placebo-controlled study, the safety, efficacy and feasibility of
oral midazolam premedication in children were evaluated in an ambulatory surgery unit …

Midazolam, a short-acting benzodiazepine, is widely used to alleviate patient anxiety,
enhance compliance, and aid in anesthesia. While its side effects are typically dose …

We report a study performed to compare the time and plasma drug concentrations
necessary to achieve a similar state of sedation after midazolam premedication given by …

The purpose of this study was to determine the influence of timing and concomitant
administration of atropine and/or meperidine on the perioperative effects of oral midazolam …

Ozalin®, a novel oral solution of 0.2% midazolam, is an effective option for moderate
sedation prior to a therapeutic or diagnostic procedure, and as premedication before …

The purpose of this study was to evaluate various doses of sublingual midazolam
premedication in children. In our prospective, double‐blind, placebo‐controlled trial …

Background: Midazolam is used as an anticonvulsant in neonatology, including newborns
with perinatal asphyxia treated with hypothermia. Hypothermia may affect the safety and …

Background Oral midazolam is widely used for preoperative sedation in children. We have
studied the pharmacokinetics (PK) of both midazolam and its active l-hydroxy metabolite and …