Oral premedication with midazolam in paediatric anaesthesia. Effects on sedation and gastric contents

J RIVA, G LEJBUSIEWICZ, M PAPA… - Pediatric …, 1997 - Wiley Online Library
The aim of this study was to assess oral premedication with midazolam in paediatric
anaesthesia. Sedation, quality of induction, recovery time, acceptance and effects on gastric …

Comparison between three transmucosal routes of administration of midazolam in children

G Geldner, M Hubmann, R Knoll… - Pediatric …, 1997 - Wiley Online Library
Midazolam was applied transmucosally in 47 children randomly assigned to three different
groups. Group N received 0.2 mg· kg− 1 nasally, group R 0.5 mg· kg− 1 rectally, and group S …

Oral midazolam with an antacid may increase the speed of onset of sedation in children prior to general anaesthesia

CR Lammers, JL Rosner, DE Crockett… - Pediatric …, 2002 - Wiley Online Library
Background: The aim of the study was to see whether sodium citrate solution would speed
the gastric absorption of oral midazolam. Methods: Forty presurgical ASA I and II patients …

Inter-individual variation in midazolam clearance in children

MI Altamimi, H Sammons, I Choonara - Archives of disease in …, 2015 - adc.bmj.com
Objectives To determine the extent of inter-individual variation in clearance of midazolam in
children and establish which factors are responsible for this variation. Methods A systematic …

Population pharmacokinetics and metabolism of midazolam in pediatric intensive care patients

SN De Wildt, M De Hoog, AA Vinks… - Critical care …, 2003 - journals.lww.com
Interventions The pharmacokinetics of midazolam and metabolites were determined during
and after a continuous infusion of midazolam (0.05–0.4 mg/kg/hr) for 3.8 hrs to 25 days …

Clinical experience with continuous intravenous sedation using midazolam and fentanyl in the paediatric intensive care unit

S Hartwig, B Roth, M Theisohn - European journal of pediatrics, 1991 - Springer
Twenty-four patients in a paediatric intensive care unit mostly undergoing cardiac surgery,
received a midazolam dosage between 50–400 μg/kg per hour as a continuous intravenous …

Comparison of induction and recovery characteristics of intravenous midazolam and thiopentone in paediatric halothane general anaesthesia

PJ Mathew, M Ravishankar, A Badhe… - Acta …, 2003 - Wiley Online Library
Fifty children were randomized for induction with 0.3 mg kg− 1 midazolam or 5 mg kg− 1
thiopentone. Efficacy, safety, recovery time, amnesic effect, tolerability and recovery …

Oral midazolam premedication for paediatric day case patients

SH Cray, JL Dixon, CMB Heard… - Pediatric …, 1996 - Wiley Online Library
Forty‐nine children having day‐stay surgical procedures were randomly assigned to receive
oral midazolam 0.75 mg· kg− 1 or placebo in a double blind fashion. The child's level of …

Midazolam for premedication in children: nasal vs. rectal administration

C Lejus, M Renaudin, S Testa… - European journal of …, 1997 - Wiley Online Library
The authors compared the acceptance and efficacy of rectal and nasal administration of
midazolam (MDZ) for premedication. Ninety‐five ASA I and II paediatric patients (8 months to …

A comparative evaluation of midazolam, clonidine and dexmedetomidine as oral premedicants in children: A double blind randomized clinical trial

S Arora, K Saini, N Bhardwaj - Anaesthesia, Pain & Intensive …, 2019 - apicareonline.com
Objective: To evaluate and compare the efficacy of orally administered midazolam, clonidine
and dexmedetomidine with regard to preoperative sedation, effect on parental separation …