[HTML][HTML] TMAO is associated with mortality: impact of modestly impaired renal function
EG Gruppen, E Garcia, MA Connelly, EJ Jeyarajah… - Scientific reports, 2017 - nature.com
Abstract Trimethylamine-N-Oxide (TMAO) is a microbiome-related metabolite that is cleared
by the kidney and linked to renal function. We explored the relationship between TMAO and …
by the kidney and linked to renal function. We explored the relationship between TMAO and …
[HTML][HTML] Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease
C Missailidis, J Hällqvist, AR Qureshi, P Barany… - PloS one, 2016 - journals.plos.org
Background The microbial metabolite Trimethylamine-N-oxide (TMAO) has been linked to
adverse cardiovascular outcome and mortality in the general population. Objective To …
adverse cardiovascular outcome and mortality in the general population. Objective To …
Gut microbiota-derived trimethylamine N-oxide is associated with the risk of all-cause and cardiovascular mortality in patients with chronic kidney disease: a …
Y Li, H Lu, J Guo, M Zhang, H Zheng, Y Liu… - Annals of …, 2023 - Taylor & Francis
Abstract Background Trimethylamine N-oxide (TMAO) derived from gut microbiota causes
kidney-heart damage in chronic kidney disease (CKD) patients. However, it is controversial …
kidney-heart damage in chronic kidney disease (CKD) patients. However, it is controversial …
[HTML][HTML] Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and …
SA Winther, JC Øllgaard, TW Hansen… - PLoS …, 2021 - journals.plos.org
Aims The trimethylamine N-oxide (TMAO) pathway is related to intestinal microbiota and has
been associated to risk of cardiovascular disease (CVD). We investigated associations …
been associated to risk of cardiovascular disease (CVD). We investigated associations …
Associations of trimethylamine N-oxide with nutritional and inflammatory biomarkers and cardiovascular outcomes in patients new to dialysis
GA Kaysen, KL Johansen, GM Chertow… - Journal of Renal …, 2015 - Elsevier
Objectives Trimethylamine N-oxide (TMAO) is a product of metabolism of
phosphatidylcholine (lecithin) and carnitine by the intestinal microbiome. Elevated serum …
phosphatidylcholine (lecithin) and carnitine by the intestinal microbiome. Elevated serum …
Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis
GG Schiattarella, A Sannino, E Toscano… - European heart …, 2017 - academic.oup.com
Aims Gut microbiota-derived metabolite trimethylamine-N-oxide (TMAO) is emerging as a
new potentially important cause of increased cardiovascular risk. The purpose of this meta …
new potentially important cause of increased cardiovascular risk. The purpose of this meta …
Gut Microbiota-Dependent Trimethylamine N-Oxide (TMAO) Pathway Contributes to Both Development of Renal Insufficiency and Mortality Risk in Chronic Kidney …
Rationale: Trimethylamine-N-oxide (TMAO), a gut microbial-dependent metabolite of dietary
choline, phosphatidylcholine (lecithin), and l-carnitine, is elevated in chronic kidney …
choline, phosphatidylcholine (lecithin), and l-carnitine, is elevated in chronic kidney …
Utility of plasma concentration of trimethylamine N-oxide in predicting cardiovascular and renal complications in individuals with type 1 diabetes
SA Winther, JC Øllgaard, N Tofte, L Tarnow… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE Trimethylamine N-oxide (TMAO) is suggested as an independent gut
microbiota–derived risk factor for cardiovascular and renal disease. We investigated …
microbiota–derived risk factor for cardiovascular and renal disease. We investigated …
[HTML][HTML] Elevation of trimethylamine-N-oxide in chronic kidney disease: contribution of decreased glomerular filtration rate
CC Pelletier, M Croyal, L Ene, A Aguesse… - Toxins, 2019 - mdpi.com
Gut microbiota-dependent Trimethylamine-N-oxide (TMAO) has been reported to be strongly
linked to renal function and to increased cardiovascular events in the general population …
linked to renal function and to increased cardiovascular events in the general population …
[PDF][PDF] A multi-omic association study of trimethylamine N-oxide
O Manor, N Zubair, MP Conomos, X Xu, JE Rohwer… - Cell reports, 2018 - cell.com
Trimethylamine N-oxide (TMAO) is a circulating metabolite that has been implicated in the
development of atherosclerosis and cardiovascular disease (CVD). In this paper, we identify …
development of atherosclerosis and cardiovascular disease (CVD). In this paper, we identify …