Association of trimethylamine N-Oxide with cardiovascular and all-cause mortality in hemodialysis patients
P Zhang, JZ Zou, J Chen, X Tan, FF Xiang, B Shen… - Renal …, 2020 - Taylor & Francis
Abstract Background Trimethylamine-N-Oxide (TMAO) is a proatherogenic and
prothrombotic metabolite. Our study examined the association of plasma TMAO level with …
prothrombotic metabolite. Our study examined the association of plasma TMAO level with …
Serum gut microbe-dependent trimethylamine N-oxide improves the prediction of future cardiovascular disease in a community-based general population
L Zheng, J Zheng, Y Xie, Z Li, X Guo, G Sun, Z Sun… - Atherosclerosis, 2019 - Elsevier
Background and aims Recent studies have shown that trimethylamine N-oxide (TMAO) is a
risk factor for cardiovascular disease (CVD) in different clinical settings, but few studies …
risk factor for cardiovascular disease (CVD) in different clinical settings, but few studies …
[HTML][HTML] The gut microbial metabolite trimethylamine N-oxide and hypertension risk: a systematic review and dose–response meta-analysis
X Ge, L Zheng, R Zhuang, P Yu, Z Xu, G Liu, X Xi… - Advances in …, 2020 - Elsevier
The gut microbial metabolite trimethylamine N-oxide (TMAO) is increasingly regarded as a
novel risk factor for cardiovascular events and mortality. However, little is known about the …
novel risk factor for cardiovascular events and mortality. However, little is known about the …
[HTML][HTML] TMAO as a potential biomarker and therapeutic target for chronic kidney disease: A review
Y Zixin, C Lulu, Z Xiangchang, F Qing… - Frontiers in …, 2022 - frontiersin.org
The gut microbiota and its metabolites have become a hotspot of recent research.
Trimethylamine N-oxide (TMAO) metabolized by the gut microbiota is closely related to …
Trimethylamine N-oxide (TMAO) metabolized by the gut microbiota is closely related to …
Trimethylamine N-oxide: a harmful, protective or diagnostic marker in lifestyle diseases?
A Nowiński, M Ufnal - Nutrition, 2018 - Elsevier
Diet has been considered a general health determinant for many years. Recent research
shows a connection between gut microbiota composition that is shaped by our diet and …
shows a connection between gut microbiota composition that is shaped by our diet and …
Gut microbial metabolite TMAO increases peritoneal inflammation and peritonitis risk in peritoneal dialysis patients
LEI Zhang, F Xie, H Tang, X Zhang, J Hu, X Zhong… - Translational …, 2022 - Elsevier
Trimethylamine-N-oxide (TMAO), a gut microbiota-produced metabolite, is accumulated in
chronic kidney disease (CKD) patients. It is well known to contribute to CKD-related …
chronic kidney disease (CKD) patients. It is well known to contribute to CKD-related …
[HTML][HTML] The association between TMAO, CMPF, and clinical outcomes in advanced chronic kidney disease: results from the European QUALity (EQUAL) Study
L Dai, ZA Massy, P Stenvinkel, NC Chesnaye… - The American Journal of …, 2022 - Elsevier
ABSTRACT Background Trimethylamine N-oxide (TMAO), a metabolite from red meat and
fish consumption, plays a role in promoting cardiovascular events. However, data regarding …
fish consumption, plays a role in promoting cardiovascular events. However, data regarding …
[HTML][HTML] Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients
KY Xu, GH Xia, JQ Lu, MX Chen, X Zhen, S Wang… - Scientific Reports, 2017 - nature.com
Chronic kidney disease (CKD) patients have an increased risk of cardiovascular diseases
(CVDs). The present study aimed to investigate the gut microbiota and blood trimethylamine …
(CVDs). The present study aimed to investigate the gut microbiota and blood trimethylamine …
Long-term changes in gut microbial metabolite trimethylamine N-oxide and coronary heart disease risk
Background A gut-microbial metabolite, trimethylamine N-oxide (TMAO), has been
associated with coronary atherosclerotic burden. No previous prospective study has …
associated with coronary atherosclerotic burden. No previous prospective study has …
Trimethylamine N-oxide and cardiovascular outcomes in patients with ESKD receiving maintenance hemodialysis
Results We observed a wide distribution of serum TMAO in our cohort, with approximately
80% of participants exhibiting TMAO concentrations≥ 56 µM and a maximum TMAO …
80% of participants exhibiting TMAO concentrations≥ 56 µM and a maximum TMAO …