Trimethylamine-N-oxide (TMAO) is a low molecular weight metabolite whose production is
dependent on metabolism of its precursors choline, carnitine, creatinine, betaine or lecithin …

Context Several studies suggest a relationship between trimethylamine N-oxide (TMAO)
concentrations and increased cardiometabolic risk, but findings are controversial. Objective …

Cardiometabolic diseases (CMDs) have been associated with changes in the composition of
the gut microbiota, with links between the host environment and microbiota identified in …

ABSTRACT Background Trimethylamine N-oxide (TMAO), a diet-derived, gut microbial-host
cometabolite, has been linked to cardiometabolic diseases. However, the relations remain …

Peripheral artery disease (PAD) is a major cause of acute and chronic illness, with extremely
poor prognosis that remains underdiagnosed and undertreated. Trimethylamine-N-Oxide …

Trimethylamine-N-oxide (TMAO) is a product of dietary, gut microbiome, and tissues
metabolism. Elevated blood TMAO levels are associated with heart attack, stroke and …

Aim Accumulating evidence has demonstrated that intestinal microbiota‐dependent
trimethylamine N‐oxide (TMAO) is involved in the pathogenesis of various cardiovascular …

The study of trimethylamine oxide (TMAO), a metabolite of gut microbiota, and heart failure
and chronic kidney disease has made preliminary achievements and been summarized by …

Chronic kidney disease (CKD) is associated with high risk for cardiovascular disease (CVD).
Gut microbiota-dependent metabolites trimethylamine (TMA), trimethylamine N-oxide …

Trimethylamine-N-oxide (TMAO), a gut-derived metabolite, has recently emerged as a
candidate risk factor for cardiovascular disease and other adverse health outcomes …