[HTML][HTML] Association of trimethylamine, trimethylamine N-oxide, and dimethylamine with cardiovascular risk in children with chronic kidney disease

CN Hsu, GP Chang-Chien, S Lin, CY Hou… - Journal of Clinical …, 2020 - mdpi.com
Chronic kidney disease (CKD) is associated with high risk for cardiovascular disease (CVD).
Gut microbiota-dependent metabolites trimethylamine (TMA), trimethylamine N-oxide …

The gut microbiome, diet, and links to cardiometabolic and chronic disorders

J Aron-Wisnewsky, K Clément - Nature Reviews Nephrology, 2016 - nature.com
Cardiometabolic diseases (CMDs) have been associated with changes in the composition of
the gut microbiota, with links between the host environment and microbiota identified in …

[HTML][HTML] Gut Microbiota-Dependent Trimethylamine-N-oxide and Serum Biomarkers in Patients with T2DM and Advanced CKD

MAI Al-Obaide, R Singh, P Datta… - Journal of clinical …, 2017 - mdpi.com
Trimethylamine-N-oxide (TMAO) is a product of dietary, gut microbiome, and tissues
metabolism. Elevated blood TMAO levels are associated with heart attack, stroke and …

Trimethylamine N-oxide: heart of the microbiota–CVD nexus?

S Naghipour, AJ Cox, JN Peart, EF Du Toit… - Nutrition research …, 2021 - cambridge.org
We critically review potential involvement of trimethylamine N-oxide (TMAO) as a link
between diet, the gut microbiota and CVD. Generated primarily from dietary choline and …

[HTML][HTML] Associations of plasma trimethylamine N-oxide, choline, carnitine, and betaine with inflammatory and cardiometabolic risk biomarkers and the fecal …

BC Fu, MAJ Hullar, TW Randolph, AA Franke… - The American journal of …, 2020 - Elsevier
ABSTRACT Background Trimethylamine N-oxide (TMAO), a compound derived from diet
and metabolism by the gut microbiome, has been associated with several chronic diseases …

[HTML][HTML] Dietary factors, gut microbiota, and serum trimethylamine-N-oxide associated with cardiovascular disease in the Hispanic Community Health Study/Study of …

Z Mei, GC Chen, Z Wang, M Usyk, B Yu… - The American journal of …, 2021 - Elsevier
ABSTRACT Background Trimethylamine-N-oxide (TMAO), a diet-derived and gut microbiota–
related metabolite, is associated with cardiovascular disease (CVD). However, major dietary …

Higher Trimethylamine-N-Oxide Plasma Levels with Increasing Age Are Mediated by Diet and Trimethylamine-Forming Bacteria

S Rath, K Rox, S Kleine Bardenhorst, U Schminke… - …, 2021 - Am Soc Microbiol
The gut microbiota-dependent metabolite trimethylamine-N-oxide (TMAO) is linked to an
increased risk for cardiovascular diseases. Trimethylamine (TMA), which is subsequently …

Plant-based diets, the gut microbiota, and trimethylamine N-oxide production in chronic kidney disease: therapeutic potential and methodological considerations

GN Wiese, A Biruete, RN Moorthi, SM Moe… - Journal of Renal …, 2021 - Elsevier
High circulating trimethylamine-N-oxide (TMAO) is associated with an increased risk of
cardiovascular disease and mortality in people with chronic kidney disease (CKD). In …

[HTML][HTML] Higher circulating Trimethylamine N-oxide levels are associated with worse severity and prognosis in pulmonary hypertension: a cohort study

Y Yang, B Yang, X Li, L Xue, B Liu, Y Liang, Z Zhao… - Respiratory …, 2022 - Springer
Abstract Background Trimethylamine N-oxide (TMAO), the gut microbiota-dependent
metabolite, is a potential biomarker in several cardiovascular diseases. However, no study …

[HTML][HTML] Gut microbiota-generated metabolite, trimethylamine-N-oxide, and subclinical myocardial damage: a multicenter study from Thailand

V Senthong, S Kiatchoosakun, C Wongvipaporn… - Scientific reports, 2021 - nature.com
Abstract Plasma Trimethylamine-N-oxide (TMAO), a gut microbiota metabolite from dietary
phosphatidylcholine, is mechanistically linked to cardiovascular disease (CVD) and adverse …