Acacetin (5, 7-dihydroxy-4'-methoxyflavone) exhibits in vitro and in vivo anticancer activity through the suppression of NF-κB/Akt signaling in prostate cancer cells
Abstract Acacetin (5, 7-dihydroxy-4'-methoxyflavone) is a flavonoid compound with
antimutagenic, antiplasmodial, antiperoxidant, anti-inflammatory and anticancer effects …
antimutagenic, antiplasmodial, antiperoxidant, anti-inflammatory and anticancer effects …
Acacetin induces apoptosis in human T cell leukemia Jurkat cells via activation of a caspase cascade
K Watanabe, SI Kanno, A Tomizawa… - Oncology …, 2012 - spandidos-publications.com
Flavonoids are naturally occurring antioxidants, with several flavonoids shown to have
chemopreventive effects on cancer. We investigated the effects of the flavonoid acacetin on …
chemopreventive effects on cancer. We investigated the effects of the flavonoid acacetin on …
Acacetin, a flavonoid, inhibits the invasion and migration of human prostate cancer DU145 cells via inactivation of the p38 MAPK signaling pathway
KH Shen, SH Hung, LT Yin, CS Huang… - Molecular and cellular …, 2010 - Springer
Abstract Acacetin (5, 7-dihydroxy-4′-methoxyflavone), a flavonoid compound, has anti-
peroxidative and anti-inflammatory effects. The effect of acacetin on antimetastasis in human …
peroxidative and anti-inflammatory effects. The effect of acacetin on antimetastasis in human …
Acacetin induces apoptosis in human osteosarcoma cells by modulation of ROS/JNK activation
S Wang, B Lin, W Liu, G Wei, Z Li, N Yu… - Drug design …, 2020 - Taylor & Francis
Purpose The long-term survival rate of osteosarcoma, which is the most common type of
primary malignant bone tumor, has stagnated in past decades. Acacetin is a natural …
primary malignant bone tumor, has stagnated in past decades. Acacetin is a natural …
The mechanism of acacetin-induced apoptosis on oral squamous cell carcinoma
CD Kim, JD Cha, SJ Li, IH Cha - Archives of oral biology, 2015 - Elsevier
Abstract Background Acacetin (5, 7-dihydroxy-40-methoxyflavone), present in safflower
seeds, plants, flowers, Cirisium rhinoceros Nakai, has been reported to be able to exert anti …
seeds, plants, flowers, Cirisium rhinoceros Nakai, has been reported to be able to exert anti …
Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: structure–activity relationship with linarin and linarin …
RP Singh, P Agrawal, D Yim, C Agarwal… - …, 2005 - academic.oup.com
This study was carried out to assess the anticancer efficacy of linarin (LN), linarin acetate
(LA) and acacetin (AC), the flavonoid compounds with the same flavone ring structure but …
(LA) and acacetin (AC), the flavonoid compounds with the same flavone ring structure but …
Acacetin-induced cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells
YL Hsu, PL Kuo, CF Liu, CC Lin - Cancer letters, 2004 - Elsevier
In this study, we examined acacetin (5, 7-dihydroxy-4′-methoxyflavone), a flavonoid
compound, for its effect on proliferation in human non-small cell lung cancer A549 cells. The …
compound, for its effect on proliferation in human non-small cell lung cancer A549 cells. The …
Induction of growth cessation by acacetin via β-catenin pathway and apoptosis by apoptosis inducing factor activation in colorectal carcinoma cells
Acacetin, a bioflavanoid, contains anti-inflammatory and anti-cancer activities as shown in
different experimental models. However, its anticancer potential and mechanism of action …
different experimental models. However, its anticancer potential and mechanism of action …
Obovatol enhances docetaxel-induced prostate and colon cancer cell death through inactivation of nuclear transcription factor-κB
SY Lee, JS Cho, DY Yuk, DC Moon, JK Jung… - Journal of …, 2009 - jstage.jst.go.jp
Nuclear transcription factor-κB (NF-κB) is constitutively activated in prostate and colon
cancers and is related with the resistance of cancer cells against chemotherapeutics …
cancers and is related with the resistance of cancer cells against chemotherapeutics …
Apoptotic induction and inhibition of NF-κB signaling pathway in human prostatic cancer PC3 cells by natural compound 2, 2′-oxybis (4-allyl-1-methoxybenzene) …
M Abbaspour Babaei, H Zaman Huri… - OncoTargets and …, 2017 - Taylor & Francis
Litsea is considered as an evergreen genus distributed in tropical and subtropical Asia; this
genus belongs to the large family of Lauraceae. In this study, the cell-death metabolism of …
genus belongs to the large family of Lauraceae. In this study, the cell-death metabolism of …