Effects of ionizing radiation on the level of genomic DNA methylation in liver, brain and
spleen of mouse as well as in two kinds of cultured cells were examined by high …

The effect of60 Co γ radiation on DNA methylation was studied in four cultured cell lines. In
all cases a dose-dependent decrease in 5-methylcytosine was observed at 24, 48, and 72 h …

It has been acknowledged for many years that radiation exposure induces delayed, non-
targeted effects in the progeny of the irradiated cell. Evidence is beginning to demonstrate …

Radiation is a well-known genotoxic agent and human carcinogen that gives rise to a variety
of long-term effects. Its detrimental influence on cellular function is actively studied …

Radiation-induced lymphomagenesis and leukemogenesis are complex processes
involving both genetic and epigenetic changes. Although genetic alterations during radiation …

Purpose: Ionizing radiation induces cellular damage through both direct and indirect
mechanisms, which may include effects from epigenetic changes. The purpose of this study …

DNA methylation is crucial for normal development, proliferation, and proper maintenance of
genome stability for a given organism. A variety of DNA damaging agents that are known to …

DNA methylation can regulate gene expression and has been shown to modulate cancer
cell biology and chemotherapy resistance. Therapeutic radiation results in a biological …

The biological and genetic effects of chronic low-dose radiation (LDR) exposure and its
relationship to carcinogenesis have received a lot of attention in the recent years. For …

The effects of ionizing radiation on DNA methylation are of importance due to the role that
DNA methylation plays in maintaining genome stability, and the presence of aberrant DNA …