While DNA cytosine methylation is relatively stable in somatic tissues, it is highly dynamic
during preimplantation development. A recent study in Nature by Meissner and colleagues …

Background The role of epigenetic modifications such as DNA methylation during vertebrate
sexual development is far from being clear. Using the zebrafish model, we tested the effects …

As one of the major epigenetic modifications, DNA methylation is constantly regulated
during embryonic development, cell lineage commitment, and pathological processes. To …

DNA methylation patterns and functions are variable across invertebrate taxa. In order to
provide a better understanding of DNA methylation in the Pacific oyster (Crassostrea gigas) …

Methylation of DNA is an essential epigenetic control mechanism in mammals. During
embryonic development, cells are directed toward their future lineages, and DNA …

DNA methylation refers to the addition of a methyl group to nucleotides within DNA. As with
other epigenetic endpoints, patterns of DNA methylation are susceptible to alterations due to …

DNA methylation is globally reprogrammed during mammalian preimplantation
development, which is critical for normal development. Recent reduced representation …

In vertebrates, epigenetic modifications influence gene transcription, and an appropriate
DNA methylation is critical in development. Indeed, a precise temporal and spatial pattern of …

An epigenetic basis for transgenerational plasticity in animals is widely theorized, but
convincing empirical support is limited by taxa-specific differences in the presence and role …

DNA methylation is a fundamental epigenetic modification in vertebrate genomes and a
small fraction of genomic regions is hypomethylated. Previous studies have implicated …