Correlated expression analysis of genes implicated in schizophrenia: identification of putative disease-related pathways
EI Liedtke, S Zhang, JA Thompson, S Sillau… - New horizons in …, 2017 - Elsevier
Schizophrenia (SCZ) is a severe psychiatric disorder affecting 0.7% of the population [1].
When inadequately treated, subjects with SCZ experience symptoms that render them …
When inadequately treated, subjects with SCZ experience symptoms that render them …
An integrative functional genomics approach for discovering biomarkers in schizophrenia
Schizophrenia (SZ) is a complex disorder resulting from both genetic and environmental
causes with a lifetime prevalence world-wide of 1%; however, there are no specific, sensitive …
causes with a lifetime prevalence world-wide of 1%; however, there are no specific, sensitive …
Genome-wide association studies of schizophrenia: does bigger lead to better results?
SE Bergen, TL Petryshen - Current opinion in psychiatry, 2012 - journals.lww.com
Identifying the genetic underpinnings of complex diseases offers insight into the etiological
mechanisms leading to manifestation of the disease. New and more effective treatments for …
mechanisms leading to manifestation of the disease. New and more effective treatments for …
[HTML][HTML] Unravelling the genetic basis of Schizophrenia
C Casey, JF Fullard, RD Sleator - Gene, 2024 - Elsevier
Neuronal development is a highly regulated mechanism that is central to organismal
function in animals. In humans, disruptions to this process can lead to a range of …
function in animals. In humans, disruptions to this process can lead to a range of …
Can the schizophrenia epigenome provide clues for the molecular basis of pathogenesis?
HM Abdolmaleky, S Thiagalingam - Epigenomics, 2011 - Taylor & Francis
Schizophrenia (SCZ), a major mental disease affecting approximately 1% of individuals
worldwide, is characterized by symptoms such as delusions, hallucinations, loosening of …
worldwide, is characterized by symptoms such as delusions, hallucinations, loosening of …
Massive schizophrenia genomics study offers new drug directions: but much more basic research on disease pathways is needed to entice more pharmaceutical …
E Dolgin - Nature reviews Drug discovery, 2014 - go.gale.com
It was an affirmation of sorts. Although the dopamine type 2 ([D. sub. 2]) receptor is a target
of all marketed antipsychotic drugs, and although focused genetic studies have tied the …
of all marketed antipsychotic drugs, and although focused genetic studies have tied the …
Overdispersed gene expression in schizophrenia
Schizophrenia (SCZ) is a severe, highly heterogeneous psychiatric disorder with varied
clinical presentations. The polygenic genetic architecture of SCZ makes identification of …
clinical presentations. The polygenic genetic architecture of SCZ makes identification of …
Molecular risk factors for schizophrenia
S Modai, N Shomron - Trends in molecular medicine, 2016 - cell.com
Schizophrenia (SZ) is a complex and strongly heritable mental disorder, which is also
associated with developmental–environmental triggers. As opposed to most diagnosable …
associated with developmental–environmental triggers. As opposed to most diagnosable …
A comprehensive family-based replication study of schizophrenia genes
Importance Schizophrenia (SCZ) is a devastating psychiatric condition. Identifying the
specific genetic variants and pathways that increase susceptibility to SCZ is critical to …
specific genetic variants and pathways that increase susceptibility to SCZ is critical to …
SZDB: a database for schizophrenia genetic research
Y Wu, YG Yao, XJ Luo - Schizophrenia bulletin, 2017 - academic.oup.com
Schizophrenia (SZ) is a debilitating brain disorder with a complex genetic architecture.
Genetic studies, especially recent genome-wide association studies (GWAS), have identified …
Genetic studies, especially recent genome-wide association studies (GWAS), have identified …