Genes are essential for the transmission of genetic information from generation to
generation, and this mechanism of inheritance is fully understood. Genes are also essential …

Cellular differentiation involves the activation of a specific set of genes as well as the
suppression of those genes associated with the differentiation of other cell types …

Understanding the mechanisms involved in the regulation of gene expression in eukaryotic
organisms is one of the major challenges facing the modern molecular biologist. Despite …

It has become apparent that the genomes of many organisms are characterized by unique
patterns of DNA methylation which can differ from genome segment to genome segment and …

Cells of a multicellular organism are genetically homogeneous but structurally and
functionally heterogeneous owing to the differential expression of genes. Many of these …

Classical genetics has revealed the mechanisms for the transmission of genes from
generation to generation, but the strategy of the genes in unfolding the developmental …

Publisher Summary The chapter discusses on the DNA methylation and its possible
biological roles. The pattern of DNA methylation is species-specific. In the DNA of some …

Publisher Summary This chapter discusses DNA methylation in eukaryotic cells. DNA
methylation pattern undergoes discrete changes, especially during the process of …

Patterns of DNA methylation in complex genomes like those of mammalian cells have been
viewed as indicators of different levels of genetic activities. It is as yet unknown how these …

Normal Mendelian genetic inheritance is based on changes in the sequence of DNA, and
these are accurately transmitted through mitosis and meiosis. Changes in sequences are …