Reversible brain abnormalities in people without signs of mountain sickness during high-altitude exposure

C Fan, Y Zhao, Q Yu, W Yin, H Liu, J Lin, T Yang… - Scientific reports, 2016 - nature.com
A large proportion of lowlanders ascending to high-altitude (HA) show no signs of mountain
sickness. Whether their brains have indeed suffered from HA environment and the persistent …

Cognitive and neuroimaging changes in healthy immigrants upon relocation to a high altitude: a panel study

X Chen, Q Zhang, J Wang, J Liu, W Zhang… - Human Brain …, 2017 - Wiley Online Library
Background Cognitive and neuroimaging changes under chronic high‐altitude exposure
have never been followed up and dynamically assessed. Objectives To investigate the …

Adaptive modulation of adult brain gray and white matter to high altitude: structural MRI studies

J Zhang, H Zhang, J Li, J Chen, Q Han, J Lin, T Yang… - PloS one, 2013 - journals.plos.org
The aim of this study was to investigate brain structural alterations in adult immigrants who
adapted to high altitude (HA). Voxel-based morphometry analysis of gray matter (GM) …

An observational cerebral magnetic resonance imaging study following 7 days at 4554 m

S Kühn, D Gerlach, HJ Noblé, F Weber… - … altitude medicine & …, 2019 - liebertpub.com
Background: In human beings exposed to high altitude, cerebral magnetic resonance
imaging (cMRI) revealed alterations ranging from subclinical cerebral edema formation to …

Combined fractional anisotropy and subcortical volumetric abnormalities in healthy immigrants to high altitude: A longitudinal study

X Chen, H Li, Q Zhang, J Wang, W Zhang… - Human brain …, 2019 - Wiley Online Library
The study of individuals at high‐altitude (HA) exposure provides an important opportunity for
unraveling physiological and psychological mechanism of brain underlying hypoxia …

Short-term high-altitude pre-exposure improves neurobehavioral ability

W Guo, G Chen, J Qin, J Zhang, X Guo, J Yu… - …, 2016 - journals.lww.com
This study aims to evaluate the effect of the duration of high-altitude (HA) pre-exposure on
human neurobehavioral parameters including mood states and cognitive performance at …

Multiparametric magnetic resonance investigation of brain adaptations to 6 days at 4350 m

S Verges, T Rupp, M Villien, L Lamalle… - Frontiers in …, 2016 - frontiersin.org
Objective: Hypoxic exposure in healthy subjects can induce acute mountain sickness
including headache, lethargy, cerebral dysfunction, and substantial cerebral structural …

Consistent differences in brain structure and functional connectivity in high-altitude native Tibetans and immigrants

X Zhang, W Xie, W Du, Y Liu, J Lin, W Yin… - Brain Imaging and …, 2023 - Springer
It has been well-established that high-altitude (HA) environments affect the human brain;
however, the differences in brain structural and functional networks between HA natives and …

A prospective evaluation of the acute effects of high altitude on cognitive and physiological functions in lowlanders

M Falla, C Papagno, T Dal Cappello, A Vögele… - Frontiers in …, 2021 - frontiersin.org
Cognitive function impairment due to high altitude exposure has been reported with some
contradictory results regarding the possible selective cognitive domain involvement. We …

[HTML][HTML] Neuronal and vascular deficits following chronic adaptation to high altitude

NP Cramer, A Korotcov, A Bosomtwi, X Xu… - Experimental …, 2019 - Elsevier
We sought to understand the mechanisms underlying cognitive deficits that are reported to
affect non-native subjects following their prolonged stay and/or work at high altitude (HA) …