Ischemic brain injury: New insights on the protective role of melatonin
Stroke represents one of the most common causes of brain's vulnerability for many millions
of people worldwide. The plethora of physiopathological events associated with brain …
of people worldwide. The plethora of physiopathological events associated with brain …
When melatonin gets on your nerves: its beneficial actions in experimental models of stroke
This article summarizes the evidence that endogenously produced and exogenously
administered melatonin reduces the degree of tissue damage and limits the biobehavioral …
administered melatonin reduces the degree of tissue damage and limits the biobehavioral …
Melatonin and ischemia–reperfusion injury of the brain
M Cervantes, G Moralí… - Journal of pineal …, 2008 - Wiley Online Library
This review summarizes the reports that have documented the neuroprotective effects of
melatonin against ischemia/reperfusion brain injury. The studies were carried out on several …
melatonin against ischemia/reperfusion brain injury. The studies were carried out on several …
Melatonin and ischemic stroke: mechanistic roles and action
SS Andrabi, S Parvez… - … in Pharmacological and …, 2015 - Wiley Online Library
Stroke is one of the most devastating neurological disabilities and brain's vulnerability
towards it proves to be fatal and socio‐economic loss of millions of people worldwide …
towards it proves to be fatal and socio‐economic loss of millions of people worldwide …
[HTML][HTML] Melatonin: a promising neuroprotective agent for cerebral ischemia-reperfusion injury
Cerebral ischemia-reperfusion (CIR) injury is initiated by the generation of reactive oxygen
species (ROS), which leads to the oxidation of cellular proteins, DNA, and lipids as an initial …
species (ROS), which leads to the oxidation of cellular proteins, DNA, and lipids as an initial …
[HTML][HTML] Systematic review of melatonin in cerebral ischemia-reperfusion injury: critical role and therapeutic opportunities
C Zhang, Y Ma, Y Zhao, N Guo, C Han, Q Wu… - Frontiers in …, 2024 - frontiersin.org
Cerebral ischemia-reperfusion (I/R) injury is the predominant causes for the poor prognosis
of ischemic stroke patients after reperfusion therapy. Currently, potent therapeutic …
of ischemic stroke patients after reperfusion therapy. Currently, potent therapeutic …
Neuroprotective mechanisms of melatonin in hemorrhagic stroke
HJ Wu, C Wu, HJ Niu, K Wang, LJ Mo, AW Shao… - Cellular and Molecular …, 2017 - Springer
Hemorrhagic stroke which consists of subarachnoid hemorrhage and intracerebral
hemorrhage is a dominant cause of death and disability worldwide. Although great efforts …
hemorrhage is a dominant cause of death and disability worldwide. Although great efforts …
The antioxidative property of melatonin against brain ischemia
I Paterniti, M Cordaro, E Esposito… - Expert Review of …, 2016 - Taylor & Francis
Introduction: This review briefly summarizes some of the large amount of data documenting
the ability of melatonin to limit molecular and organ tissue damage in neural ischemia …
the ability of melatonin to limit molecular and organ tissue damage in neural ischemia …
The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion
RTF Cheung - Journal of pineal research, 2003 - Wiley Online Library
The brain is highly susceptible to focal or global ischemia. Unless ischemia is promptly
reversed, reperfusion produces further cerebral damage. Acute thrombolysis or …
reversed, reperfusion produces further cerebral damage. Acute thrombolysis or …
Effects of melatonin in experimental stroke models in acute, sub-acute, and chronic stages
HW Lin, EJ Lee - Neuropsychiatric disease and treatment, 2009 - Taylor & Francis
Melatonin (n-acetyl-5-methoxy-tryptamine), a naturally occurring indole produced mainly by
the pineal gland, is a well known antioxidant. Stroke (cerebral ischemia) is the second …
the pineal gland, is a well known antioxidant. Stroke (cerebral ischemia) is the second …