The effect of isocapnic hyperoxia on neurophysiology as measured with MRI and MEG
The physiological effect of hyperoxia has been poorly characterize d, with studies reporting
conflicting results on the role of hyperoxia as a vasoconstrictor. It is not clear whether …
conflicting results on the role of hyperoxia as a vasoconstrictor. It is not clear whether …
Are the local Blood Oxygen Level–Dependent (BOLD) signals caused by neural stimulation response dependent on global BOLD signals induced by hypercapnia in …
YJ Liu, CJ Juan, CY Chen, CY Wang… - American journal …, 2007 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The relationship between the local blood oxygen level–
dependent (BOLD) signals caused by neural stimulation (fBOLD) and the global BOLD …
dependent (BOLD) signals caused by neural stimulation (fBOLD) and the global BOLD …
Searching for a truly “iso-metabolic” gas challenge in physiological MRI
Hypercapnia challenge (eg inhalation of CO2) has been used in calibrated fMRI as well as
in the mapping of vascular reactivity in cerebrovascular diseases. An important assumption …
in the mapping of vascular reactivity in cerebrovascular diseases. An important assumption …
Cerebral blood flow and BOLD fMRI responses to hypoxia in awake and anesthetized rats
TQ Duong - Brain research, 2007 - Elsevier
This study investigated the functional MRI responses to graded hypoxia in awake/restrained
and anesthetized animals by measuring cerebral blood flow (CBF) and blood oxygenation …
and anesthetized animals by measuring cerebral blood flow (CBF) and blood oxygenation …
The influence of moderate hypercapnia on neural activity in the anesthetized nonhuman primate
Hypercapnia is often used as vasodilatory challenge in clinical applications and basic
research. In functional magnetic resonance imaging (fMRI), elevated CO2 is applied to …
research. In functional magnetic resonance imaging (fMRI), elevated CO2 is applied to …
Effect of hypoxia and hyperoxia on cerebral blood flow, blood oxygenation, and oxidative metabolism
Characterizing the effect of oxygen (O2) modulation on the brain may provide a better
understanding of several clinically relevant problems, including acute mountain sickness …
understanding of several clinically relevant problems, including acute mountain sickness …
Haemodynamic and neural responses to hypercapnia in the awake rat
The relationship between localized changes in brain activity and metabolism, and the blood
oxygenation level‐dependent (BOLD) signal used in functional magnetic resonance …
oxygenation level‐dependent (BOLD) signal used in functional magnetic resonance …
Elevated CO2 mitigates the rise in CMRO2 during acute hypoxia and improves cerebral tissue oxygenation
ZM Smith, JS Hunt, E Li, J Guo, DD Shin… - Proceeding of the …, 2011 - archive.ismrm.org
We previously reported increased CMRO2 during sustained hypoxia, despite limited O2
availability. The biological rationale for this paradoxical response remains unclear. To …
availability. The biological rationale for this paradoxical response remains unclear. To …
Regional cerebrovascular responses to hypercapnia and hypoxia
DR Corfield, LC McKay - Hypoxia: Translation in Progress, 2016 - Springer
A limited number of studies using differing imaging approaches suggest that there are
regional variation in the cerebrovascular response to hypercapnia and hypoxia. However …
regional variation in the cerebrovascular response to hypercapnia and hypoxia. However …
The Cumulative Influence of Hyperoxia and Hypercapnia on Blood Oxygenation and R2*
CC Faraco, MK Strother, JCW Siero… - Journal of Cerebral …, 2015 - journals.sagepub.com
Cerebrovascular reactivity (CVR)-weighted blood-oxygenation-level-dependent magnetic
resonance imaging (BOLD-MRI) experiments are frequently used in conjunction with …
resonance imaging (BOLD-MRI) experiments are frequently used in conjunction with …