Background and objective Imprinted genes are important for the offspring development. To
assess the relationship between obesity-related H19DMR methylation and H19 and IGF2 …

Background Data from epidemiological and animal model studies suggest that nutrition
during pregnancy may affect the health status of subsequent generations. These …

Background The insulin-like growth factor 2 (IGF2) and H19 imprinted genes control growth
and body composition. Adverse in-utero environments have been associated with obesity …

Background: Several epidemiologic studies have demonstrated associations between
periconceptional environmental exposures and health status of the offspring in later life …

Over the past four decades, the global prevalence of obesity has increased rapidly in all age
ranges. Emerging evidence suggests that paternal lifestyle and environmental exposure …

The insulin-like growth factor 2 (IGF2) gene, located within a cluster of imprinted genes on
chromosome 11p15, encodes a fetal and placental growth factor affecting birth weight. DNA …

Changes in epigenetic programming of embryonic growth genes during pregnancy seem to
affect fetal growth. Therefore, in a population-based prospective birth cohort in the …

OBJECTIVE: To determine whether aberrant DNA methylation at differentially methylated
regions (DMRs) regulating insulin-like growth factor 2 (IGF2) expression in umbilical cord …

Epigenetic regulation of imprinted genes is regarded as a highly plausible explanation for
linking dietary exposures in early life with the onset of diseases during childhood and …

Objectives To study DNA methylation at the C19MC locus in the placenta and its association
with (1) parental body size,(2) transmission of haplotypes for the C19MC rs55765443 SNP …