Polycomb complexes and epigenetic states
YB Schwartz, V Pirrotta - Current opinion in cell biology, 2008 - Elsevier
Important advances in the study of Polycomb Group (PcG) complexes in the past two years
have focused on the role of this repressive system in programing the genome. Genome-wide …
have focused on the role of this repressive system in programing the genome. Genome-wide …
A new world of Polycombs: unexpected partnerships and emerging functions
YB Schwartz, V Pirrotta - Nature Reviews Genetics, 2013 - nature.com
Polycomb group (PcG) proteins are epigenetic repressors that are essential for the
transcriptional control of cell differentiation and development. PcG-mediated repression is …
transcriptional control of cell differentiation and development. PcG-mediated repression is …
Context-specific Polycomb mechanisms in development
JJ Kim, RE Kingston - Nature Reviews Genetics, 2022 - nature.com
Polycomb group (PcG) proteins are crucial chromatin regulators that maintain repression of
lineage-inappropriate genes and are therefore required for stable cell fate. Recent advances …
lineage-inappropriate genes and are therefore required for stable cell fate. Recent advances …
Polycomb group complexes–many combinations, many functions
TK Kerppola - Trends in cell biology, 2009 - cell.com
Polycomb Group (PcG) proteins are transcription regulatory proteins that control the
expression of a variety of genes from early embryogenesis through birth to adulthood. PcG …
expression of a variety of genes from early embryogenesis through birth to adulthood. PcG …
Regulation of gene transcription by Polycomb proteins
S Aranda, G Mas, L Di Croce - Science advances, 2015 - science.org
The Polycomb group (PcG) of proteins defines a subset of factors that physically associate
and function to maintain the positional identity of cells from the embryo to adult stages. PcG …
and function to maintain the positional identity of cells from the embryo to adult stages. PcG …
Programming of gene expression by Polycomb group proteins
C Köhler, CBR Villar - Trends in cell biology, 2008 - cell.com
Polycomb group (PcG) complexes maintain epigenetically repressed states that need to be
reprogrammed when cells become committed to differentiation. In contrast to the previously …
reprogrammed when cells become committed to differentiation. In contrast to the previously …
Concise review: roles of polycomb group proteins in development and disease: a stem cell perspective
VK Rajasekhar, M Begemann - Stem cells, 2007 - academic.oup.com
The acquisition and maintenance of cell fate are essential for metazoan growth and
development. A strict coordination between genetic and epigenetic programs regulates cell …
development. A strict coordination between genetic and epigenetic programs regulates cell …
Division of labor in polycomb group repression
The epigenetic maintenance of gene expression patterns is essential for developing and
maintaining the diverse types of cell that cooperate to form the larger organism. Recent data …
maintaining the diverse types of cell that cooperate to form the larger organism. Recent data …
Biochemical mechanisms of gene regulation by polycomb group protein complexes
J Müller, P Verrijzer - Current opinion in genetics & development, 2009 - Elsevier
Polycomb group (PcG) proteins are transcriptional repressors that control expression of
developmental regulator genes in animals and plants. Recent advances in our …
developmental regulator genes in animals and plants. Recent advances in our …
Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice
B Schuettengruber, G Cavalli - Development, 2009 - journals.biologists.com
Polycomb group (PcG) protein complexes dynamically define cellular identity through the
regulation of key developmental genes. Important advances in the PcG field have come from …
regulation of key developmental genes. Important advances in the PcG field have come from …