[PDF][PDF] DNA methylation signatures within the human brain
C Ladd-Acosta, J Pevsner, S Sabunciyan… - The American Journal of …, 2007 - cell.com
DNA methylation is a heritable modification of genomic DNA central to development,
imprinting, transcriptional regulation, chromatin structure, and overall genomic stability …
imprinting, transcriptional regulation, chromatin structure, and overall genomic stability …
Population-specificity of human DNA methylation
Background Ethnic differences in human DNA methylation have been shown for a number of
CpG sites, but the genome-wide patterns and extent of these differences are largely …
CpG sites, but the genome-wide patterns and extent of these differences are largely …
Tissue-specific variation in DNA methylation levels along human chromosome 1
Background DNA methylation is a major epigenetic modification important for regulating
gene expression and suppressing spurious transcription. Most methods to scan the genome …
gene expression and suppressing spurious transcription. Most methods to scan the genome …
[PDF][PDF] Genetic control of individual differences in gene-specific methylation in human brain
We have observed extensive interindividual differences in DNA methylation of 8590 CpG
sites of 6229 genes in 153 human adult cerebellum samples, enriched in CpG island" …
sites of 6229 genes in 153 human adult cerebellum samples, enriched in CpG island" …
[HTML][HTML] Comparison of whole-genome DNA methylation patterns in whole blood, saliva, and lymphoblastoid cell lines
TM Thompson, D Sharfi, M Lee, CM Yrigollen… - Behavior genetics, 2013 - Springer
Epigenetic mechanisms, including DNA methylation, that underlie neuropsychiatric
conditions have become a promising area of research. Most commonly used DNA sources …
conditions have become a promising area of research. Most commonly used DNA sources …
Dynamic DNA methylation across diverse human cell lines and tissues
As studies of DNA methylation increase in scope, it has become evident that methylation has
a complex relationship with gene expression, plays an important role in defining cell types …
a complex relationship with gene expression, plays an important role in defining cell types …
[PDF][PDF] DNA methylation signatures in development and aging of the human prefrontal cortex
S Numata, T Ye, TM Hyde, X Guitart-Navarro… - The American Journal of …, 2012 - cell.com
The human prefrontal cortex (PFC), a mastermind of the brain, is one of the last brain
regions to mature. To investigate the role of epigenetics in the development of PFC, we …
regions to mature. To investigate the role of epigenetics in the development of PFC, we …
Distinct DNA methylation changes highly correlated with chronological age in the human brain
Methylation at CpG sites is a critical epigenetic modification in mammals. Altered DNA
methylation has been suggested to be a central mechanism in development, some disease …
methylation has been suggested to be a central mechanism in development, some disease …
Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns
E Schneider, G Pliushch, N El Hajj… - Nucleic acids …, 2010 - academic.oup.com
DNA methylation is an epigenetic modification that plays an important role in gene
regulation. It can be influenced by stochastic events, environmental factors and …
regulation. It can be influenced by stochastic events, environmental factors and …
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue-and individual-specific DNA methylation patterns
HM Byun, KD Siegmund, F Pan… - Human molecular …, 2009 - academic.oup.com
DNA methylation is known to be associated with cell differentiation, aging, disease and
cancer. There exists an expanding base of knowledge regarding tissue-specific DNA …
cancer. There exists an expanding base of knowledge regarding tissue-specific DNA …
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