Mammalian DNA methyltransferases (DNMTs) establish and maintain genomic DNA
methylation patterns that are required for proper epigenetic regulation of gene expression …

DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …

DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …

DNA methylation is a major epigenetic regulatory mechanism for gene expression and cell
differentiation. Until recently, it was still unclear how unmethylated regions in mammalian …

DNA methylation, a modification found in most species, regulates chromatin functions in
conjunction with other epigenome modifications, such as histone post-translational …

Methylation of cytosines in the mammalian genome represents a key epigenetic modification
and is dynamically regulated during development. Compelling evidence now suggests that …

DNA methyltransferases (DNMTs) establish and maintain DNA methylation patterns at
specific regions of the genome, thereby contributing to gene regulation. It is becoming …

DNA methylation at the 5-position of cytosine (5mC) plays vital roles in mammalian
development. DNA methylation is catalyzed by DNA methyltransferases (DNMTs), and the …

DNA methylation plays a pivotal role during development in mammals and is central to
transcriptional silencing. The DNA methyltransferases (DNMTs) are responsible for the …

DNA methylation is one of the most extensively studied epigenetic marks. It is involved in
transcriptional gene silencing and plays important roles during mammalian development. Its …