Update on C3 glomerulopathy: a complement-mediated disease

F Caravaca-Fontán, L Lucientes, T Cavero, M Praga - Nephron, 2020 - karger.com
Abstract C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of
the alternative complement pathway in plasma and the glomerular microenvironment. The …

C3 glomerulopathy and current dilemmas

N Ito, R Ohashi, M Nagata - Clinical and experimental nephrology, 2017 - Springer
Abstract C3 glomerulopathy (C3G) is a recently identified disease entity caused by
dysregulation of the alternative complement pathway, and dense deposit disease (DDD) …

[HTML][HTML] C3 glomerulopathy

HT Cook - F1000Research, 2017 - ncbi.nlm.nih.gov
C3 glomerulopathy is a recently defined entity that encompasses a group of kidney diseases
caused by abnormal control of complement activation with deposition of complement …

[HTML][HTML] C3 glomerulopathy: consensus report

MC Pickering, VD D'agati, CM Nester, RJ Smith… - Kidney international, 2013 - Elsevier
C3 glomerulopathy is a recently introduced pathological entity whose original definition was
glomerular pathology characterized by C3 accumulation with absent or scanty …

C3 glomerulopathy: pathogenesis and treatment

SB Ahmad, AS Bomback - Advances in Chronic Kidney Disease, 2020 - Elsevier
C3 glomerulopathy (C3G) is a rare set of kidney diseases with 2 patterns: C3
glomerulonephritis (C3GN) and dense deposit disease. Pathogenesis of both diseases is …

Results from a nationwide retrospective cohort measure the impact of C3 and soluble C5b-9 levels on kidney outcomes in C3 glomerulopathy

S Chauvet, JJ Hauer, F Petitprez, M Rabant… - Kidney international, 2022 - Elsevier
C3 glomerulopathy (C3G) is a rare complement-mediated disease. Specific treatments are
not yet available and factors predictive of kidney survival such as age, kidney function and …

C3 glomerulopathy—understanding a rare complement-driven renal disease

RJH Smith, GB Appel, AM Blom, HT Cook… - Nature reviews …, 2019 - nature.com
The C3 glomerulopathies are a group of rare kidney diseases characterized by complement
dysregulation occurring in the fluid phase and in the glomerular microenvironment, which …

C3 glomerulopathy: the genetic and clinical findings in dense deposit disease and C3 glomerulonephritis

X Xiao, MC Pickering, RJH Smith - Seminars in thrombosis and …, 2014 - thieme-connect.com
C3 glomerulopathy (C3G) defines a group of very rare renal diseases in which dysregulation
of the alternative and terminal complement pathways plays a pivotal pathogenic role …

Complement inhibition in C3 glomerulopathy

CM Nester, RJH Smith - Seminars in immunology, 2016 - Elsevier
Abstract C3 glomerulopathy (C3G) describes a spectrum of glomerular diseases defined by
shared renal biopsy pathology: a predominance of C3 deposition on immunofluorescence …

C3 glomerulopathy: understanding an ultra‐rare complement‐mediated renal disease

AK Heiderscheit, JJ Hauer… - American Journal of …, 2022 - Wiley Online Library
Abstract C3 glomerulopathy (C3G) describes a pathologic pattern of injury diagnosed by
renal biopsy. It is characterized by the dominant deposition of the third component of …