Although the field of genetics has grown by leaps and bounds within the last decade due to
the completion and availability of the human genome sequence, transcriptional regulation …

DNA methylation is important in the control of gene transcription and chromatin structure.
The complexities of this process are just beginning to be elucidated in relationship to other …

Over three decades ago DNA methylation had been suggested to play a role in the
regulation of gene expression. This chapter reviews the development of this field of research …

Both DNA methylation and histone modification are involved in establishing patterns of gene
repression during development. Certain forms of histone methylation cause local formation …

In the past few years, there has been a nascent convergence of scientific understanding of
inherited human diseases with epigenetics. Identified epigenetic processes involved in …

Epigenetic regulation is the mechanism by which gene function is selectively activated or
inactivated in the cells. It provides higher-ordered and more specified genetic information …

Organisms require an appropriate balance of stability and reversibility in gene expression
programmes to maintain cell identity or to enable responses to stimuli; epigenetic regulation …

Epigenetics is the study of heritable and stable changes in gene expression that occur
through alterations in the chromosome rather than in the DNA sequence. Despite not directly …

Methylation of histones mediates transcriptional silencing at heterochromatin sites and
affects regulated transcription at euchromatic loci. So is the methyl group a permanent mark …

Cells of a multicellular organism are genetically homogeneous but structurally and
functionally heterogeneous owing to the differential expression of genes. Many of these …