Genome-wide DNA methylation profiling using Infinium® assay
M Bibikova, J Le, B Barnes, S Saedinia-Melnyk… - …, 2009 - Taylor & Francis
Aims: Bisulfite sequence analysis of individual CpG sites within genomic DNA is a powerful
approach for methylation analysis in the genome. The major limitation of bisulfite-based …
approach for methylation analysis in the genome. The major limitation of bisulfite-based …
The correlation of methylation levels measured using Illumina 450K and EPIC BeadChips in blood samples
Aim: We examined concordance of methylation levels across the Illumina Infinium
HumanMethylation450 BeadChip and the Infinium MethylationEPIC BeadChip. Methods …
HumanMethylation450 BeadChip and the Infinium MethylationEPIC BeadChip. Methods …
Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array
Background There has been a steady increase in the number of studies aiming to identify
DNA methylation differences associated with complex phenotypes. Many of the challenges …
DNA methylation differences associated with complex phenotypes. Many of the challenges …
MethylAid: visual and interactive quality control of large Illumina 450k datasets
The Illumina 450k array is a frequently used platform for large-scale genome-wide DNA
methylation studies, ie epigenome-wide association studies. Currently, quality control of …
methylation studies, ie epigenome-wide association studies. Currently, quality control of …
[HTML][HTML] shinyMethyl: interactive quality control of Illumina 450k DNA methylation arrays in R
We present shinyMethyl, a Bioconductor package for interactive quality control of DNA
methylation data from Illumina 450k arrays. The package summarizes 450k experiments into …
methylation data from Illumina 450k arrays. The package summarizes 450k experiments into …
Review of processing and analysis methods for DNA methylation array data
CS Wilhelm-Benartzi, DC Koestler, MR Karagas… - British journal of …, 2013 - nature.com
The promise of epigenome-wide association studies and cancer-specific somatic DNA
methylation changes in improving our understanding of cancer, coupled with the decreasing …
methylation changes in improving our understanding of cancer, coupled with the decreasing …
Base resolution methylome profiling: considerations in platform selection, data preprocessing and analysis
Bisulfite treatment-based methylation microarray (mainly Illumina 450K Infinium array) and
next-generation sequencing (reduced representation bisulfite sequencing, Agilent …
next-generation sequencing (reduced representation bisulfite sequencing, Agilent …
Comprehensive high-throughput arrays for relative methylation (CHARM)
This study was originally conceived to test in a rigorous way the specificity of three major
approaches to high-throughput array-based DNA methylation analysis:(1) MeDIP, or …
approaches to high-throughput array-based DNA methylation analysis:(1) MeDIP, or …
DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns
Background DNA epigenetic modifications, such as methylation, are important regulators of
tissue differentiation, contributing to processes of both development and cancer. Profiling the …
tissue differentiation, contributing to processes of both development and cancer. Profiling the …
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
DNA methylation plays key roles in diverse biological processes such as X chromosome
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …