[HTML][HTML] Profiling genome-wide DNA methylation

WS Yong, FM Hsu, PY Chen - Epigenetics & chromatin, 2016 - Springer
DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …

A statistical framework for Illumina DNA methylation arrays

PF Kuan, S Wang, X Zhou, H Chu - Bioinformatics, 2010 - academic.oup.com
Abstract Motivation: The Illumina BeadArray is a popular platform for profiling DNA
methylation, an important epigenetic event associated with gene silencing and …

An evaluation of supervised methods for identifying differentially methylated regions in Illumina methylation arrays

S Mallik, GJ Odom, Z Gao, L Gomez… - Briefings in …, 2019 - academic.oup.com
Epigenome-wide association studies (EWASs) have become increasingly popular for
studying DNA methylation (DNAm) variations in complex diseases. The Illumina methylation …

[HTML][HTML] Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER

HED Suchiman, RC Slieker, D Kremer… - Frontiers in …, 2015 - frontiersin.org
EpiTYPER® is a mass spectrometry-based bisulfite sequencing method that enables region-
specific DNA methylation analysis in a quantitative and high-throughput fashion. The …

[PDF][PDF] DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse

W Zhou, T Hinoue, B Barnes, O Mitchell, W Iqbal… - Cell genomics, 2022 - cell.com
We have developed a mouse DNA methylation array that contains 296,070 probes
representing the diversity of mouse DNA methylation biology. We present a mouse …

Comparison of DNA methylation measured by Illumina 450K and EPIC BeadChips in blood of newborns and 14-year-old children

O Solomon, J MacIsaac, H Quach, G Tindula… - Epigenetics, 2018 - Taylor & Francis
Analysis of DNA methylation helps to understand the effects of environmental exposures as
well as the role of epigenetics in human health. Illumina, Inc. recently replaced the …

[HTML][HTML] Evaluating DNA methylation age on the illumina MethylationEPIC bead chip

R Dhingra, LC Kwee, D Diaz-Sanchez, RB Devlin… - PloS one, 2019 - journals.plos.org
DNA methylation age (DNAm age) has become a widely utilized epigenetic biomarker for
the aging process. The Horvath method for determining DNAm age is perhaps the most …

[HTML][HTML] An evaluation of processing methods for HumanMethylation450 BeadChip data

J Liu, KD Siegmund - BMC genomics, 2016 - Springer
Abstract Background Illumina's HumanMethylation450 arrays provide the most cost-effective
means of high-throughput DNA methylation analysis. As with other types of microarray …

A comprehensive overview of Infinium HumanMethylation450 data processing

S Dedeurwaerder, M Defrance, M Bizet… - Briefings in …, 2014 - academic.oup.com
Infinium HumanMethylation450 beadarray is a popular technology to explore DNA
methylomes in health and disease, and there is a current explosion in the use of this …

[PDF][PDF] Mapping the methylome

EV Epigenomics - Cell Cycle, 2006 - researchgate.net
ABSTRACT DNA methylation is integral to normal development and disease processes.
However, the genomic distribution of methylated sequences—the methylome—is poorly …