Neurosensory responses of hearing and balance are mediated by receptors in specialized
neuroepithelial sensory cells. Any disruption of the biochemical and molecular pathways …

Millions of people worldwide suffer from hearing and balance disorders caused by loss of
the sensory hair cells that convert sound vibrations and head movements into electrical …

Mammalian inner ear hair cells do not have the ability to spontaneously regenerate, so their
irreversible damage is the main cause of sensorineural hearing loss. The damage and loss …

Sensorineural hearing loss (SNHL) is typically a permanent and often progressive condition
that is commonly attributed to sensory cell loss. All vertebrates except mammals can …

Sensory hair cells of the inner ear are responsible for translating auditory or vestibular
stimuli into electrical energy that can be perceived by the nervous system. Although hair …

Deafness or hearing deficits are debilitating conditions. They are often caused by loss of
sensory hair cells or defects in their function. In contrast to mammals, nonmammalian …

Cochlear hair cells are mechanoreceptors of the auditory system and cannot spontaneously
regenerate in adult mammals; thus hearing loss due to hair cell damage is permanent. In …

Purpose To provide an overview of the methodologies involved in the field of hair cell
regeneration. First, the author provides a tutorial on the biotechnological foundations of this …

Sensory hair cells of the inner ear are susceptible to damage from a variety of sources
including aging, genetic defects, and environmental stresses such as loud noises or …

Hearing loss is a global health problem with profound socioeconomic impact. We contend
that acquired hearing loss is mainly a modern disorder caused by man-made noise and …