Batch effect correction for genome-wide methylation data with Illumina Infinium platform
Background Genome-wide methylation profiling has led to more comprehensive insights
into gene regulation mechanisms and potential therapeutic targets. Illumina Human …
into gene regulation mechanisms and potential therapeutic targets. Illumina Human …
A systematic study of normalization methods for Infinium 450K methylation data using whole-genome bisulfite sequencing data
DNA methylation plays an important role in disease etiology. The Illumina Infinium
HumanMethylation450 (450K) BeadChip is a widely used platform in large-scale …
HumanMethylation450 (450K) BeadChip is a widely used platform in large-scale …
Evaluation of pre-processing on the meta-analysis of DNA methylation data from the Illumina HumanMethylation450 BeadChip platform
Introduction Meta-analysis is a powerful means for leveraging the hundreds of experiments
being run worldwide into more statistically powerful analyses. This is also true for the …
being run worldwide into more statistically powerful analyses. This is also true for the …
Meffil: efficient normalisation and analysis of very large DNA methylation samples
Background Technological advances in high throughput DNA methylation microarrays have
allowed dramatic growth of a new branch of epigenetic epidemiology. DNA methylation …
allowed dramatic growth of a new branch of epigenetic epidemiology. DNA methylation …
Adjusting for batch effects in DNA methylation microarray data, a lesson learned
EM Price, WP Robinson - Frontiers in genetics, 2018 - frontiersin.org
It is well-known, but frequently overlooked, that low-and high-throughput molecular data may
contain batch effects, ie, systematic technical variation. Confounding of experimental …
contain batch effects, ie, systematic technical variation. Confounding of experimental …
Removing unwanted variation in a differential methylation analysis of Illumina HumanMethylation450 array data
J Maksimovic, JA Gagnon-Bartsch… - Nucleic acids …, 2015 - academic.oup.com
Due to their relatively low-cost per sample and broad, gene-centric coverage of CpGs across
the human genome, Illumina's 450k arrays are widely used in large scale differential …
the human genome, Illumina's 450k arrays are widely used in large scale differential …
A systematic assessment of normalization approaches for the Infinium 450K methylation platform
The Illumina Infinium HumanMethylation450 BeadChip has emerged as one of the most
popular platforms for genome wide profiling of DNA methylation. While the technology is …
popular platforms for genome wide profiling of DNA methylation. While the technology is …
Batch-effect detection, correction and characterisation in Illumina HumanMethylation450 and MethylationEPIC BeadChip array data
Background Genomic technologies can be subject to significant batch-effects which are
known to reduce experimental power and to potentially create false positive results. The …
known to reduce experimental power and to potentially create false positive results. The …
Characterisation and reproducibility of the HumanMethylationEPIC v2. 0 BeadChip for DNA methylation profiling
TJ Peters, B Meyer, L Ryan, J Achinger-Kawecka… - BMC genomics, 2024 - Springer
Abstract Background The Illumina family of Infinium Methylation BeadChip microarrays has
been widely used over the last 15 years for genome-wide DNA methylation profiling …
been widely used over the last 15 years for genome-wide DNA methylation profiling …
A data-driven approach to preprocessing Illumina 450K methylation array data
Background As the most stable and experimentally accessible epigenetic mark, DNA
methylation is of great interest to the research community. The landscape of DNA …
methylation is of great interest to the research community. The landscape of DNA …