Variant Histone H2afv reprograms DNA methylation during early zebrafish development
B Madakashira, L Corbett, C Zhang, P Paoli… - Epigenetics, 2017 - Taylor & Francis
The DNA methylome is re-patterned during discrete phases of vertebrate development. In
zebrafish, there are 2 waves of global DNA demethylation and re-methylation: the first …
zebrafish, there are 2 waves of global DNA demethylation and re-methylation: the first …
Developmental features of DNA methylation during activation of the embryonic zebrafish genome
Background Zygotic genome activation (ZGA) occurs at the mid-blastula transition (MBT) in
zebrafish and is a period of extensive chromatin remodeling. Genome-scale gametic …
zebrafish and is a period of extensive chromatin remodeling. Genome-scale gametic …
Global changes in genomic methylation levels during early development of the zebrafish embryo
AA Mhanni, RA McGowan - Development genes and evolution, 2004 - Springer
We have examined the methylation status of the zebrafish genome during early
embryogenesis and we find evidence that methylation fluxes do occur in that organism. The …
embryogenesis and we find evidence that methylation fluxes do occur in that organism. The …
Embryonic DNA methylation: insights from the genomics era
O Bogdanović… - Briefings in functional …, 2014 - academic.oup.com
DNA methylation is an epigenetic mark associated with transcriptional repression and
essential for proper vertebrate development. Because of its association with human …
essential for proper vertebrate development. Because of its association with human …
Reprogramming histone modification patterns to coordinate gene expression in early zebrafish embryos
W Zhu, X Xu, X Wang, J Liu - BMC genomics, 2019 - Springer
Background Multicellular organisms require precise gene regulation during ontogeny, and
epigenetic modifications, such as DNA methylation and histone modification, facilitate this …
epigenetic modifications, such as DNA methylation and histone modification, facilitate this …
Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos
DNA methylation undergoes dynamic changes during development and cell differentiation.
Recent genome-wide studies discovered that tissue-specific differentially methylated …
Recent genome-wide studies discovered that tissue-specific differentially methylated …
A role for DNA methylation in gastrulation and somite patterning
CC Martin, L Laforest, MA Akimenko, M Ekker - Developmental biology, 1999 - Elsevier
DNA methylation constitutes an important epigenetic factor in the control of genetic
information. In this study, we analyzed expression of the DNA methyltransferase gene and …
information. In this study, we analyzed expression of the DNA methyltransferase gene and …
Immunological detection of changes in genomic DNA methylation during early zebrafish development
AB MacKay, AA Mhanni, RA McGowan, PH Krone - Genome, 2007 - cdnsciencepub.com
DNA methylation reprogramming, the erasure of DNA methylation patterns shortly after
fertilization and their reestablishment during subsequent early development, is essential for …
fertilization and their reestablishment during subsequent early development, is essential for …
Chromatin states of developmentally-regulated genes revealed by DNA and histone methylation patterns in zebrafish embryos.
Embryo development proceeds from a cascade of gene activation and repression events
controlled by epigenetic modifications of DNA and histones. Little is known about epigenetic …
controlled by epigenetic modifications of DNA and histones. Little is known about epigenetic …
Large hypomethylated domains serve as strong repressive machinery for key developmental genes in vertebrates
R Nakamura, T Tsukahara, W Qu, K Ichikawa… - …, 2014 - journals.biologists.com
DNA methylation is a fundamental epigenetic modification in vertebrate genomes and a
small fraction of genomic regions is hypomethylated. Previous studies have implicated …
small fraction of genomic regions is hypomethylated. Previous studies have implicated …
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