Obstacles and opportunities in a forward vision for cancer nanomedicine

I de Lázaro, DJ Mooney - Nature materials, 2021 - nature.com
Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …

Nanomedicine tumor targeting

T Lammers - Advanced Materials, 2024 - Wiley Online Library
Nanomedicines are extensively explored for cancer therapy. By delivering drug molecules
more efficiently to pathological sites and by attenuating their accumulation in healthy organs …

Cancer nanomedicine: is targeting our target?

T Lammers, F Kiessling, M Ashford, W Hennink… - Nature Reviews …, 2016 - nature.com
The majority of nanomedicines in (pre) clinical trials are based on established drugs, such
as doxorubicin and paclitaxel. Does that make sense? To some extent yes, because a lot of …

Translating nanomedicines for anti-cancer treatment

K Siram, HH Amin, N Meghani, H Rahman… - Frontiers in …, 2023 - frontiersin.org
Nanomedicine is a rapidly emerging field that holds great promise for the treatment of
cancer. Nanomedicine has the potential to completely alter the way cancer is treated since it …

Nano-based approved pharmaceuticals for cancer treatment: present and future challenges

F Rodríguez, P Caruana, N De la Fuente, P Español… - Biomolecules, 2022 - mdpi.com
Cancer is one of the main causes of death worldwide. To date, and despite the advances in
conventional treatment options, therapy in cancer is still far from optimal due to the non …

Nanomedicine: Innovative Strategies and Recent Advances in Targeted Cancer Therapy

R Gautam, P Mittal, R Goyal, K Dua… - Current Medicinal …, 2024 - ingentaconnect.com
Nanomedicine's application of nanotechnology in medicine holds tremendous potential for
diagnosing and treating life-threatening diseases such as cancer. Unlike conventional …

Tumor‐targeted nanotherapeutics: overcoming treatment barriers for glioblastoma

AS Wadajkar, JG Dancy, DS Hersh… - Wiley …, 2017 - Wiley Online Library
Glioblastoma (GBM) is a highly aggressive and lethal form of primary brain cancer.
Numerous barriers exist to the effective treatment of GBM including the tightly controlled …

Nanomedicines for cancer therapy: state-of-the-art and limitations to pre-clinical studies that hinder future developments

CM Dawidczyk, LM Russell, PC Searson - Frontiers in chemistry, 2014 - frontiersin.org
The ability to efficiently deliver a drug or gene to a tumor site is dependent on a wide range
of factors including circulation time, interactions with the mononuclear phagocyte system …

Nanotechnology for cancer treatment

WH Gmeiner, S Ghosh - Nanotechnology reviews, 2014 - degruyter.com
Nanotechnology has the potential to increase the selectivity and potency of chemical,
physical, and biological approaches for eliciting cancer cell death while minimizing …

Nanomedicine: The promise and challenges in cancer chemotherapy

YW Naguib, Z Cui - Nanomaterial: Impacts on Cell Biology and Medicine, 2014 - Springer
Cancer is a leading cause of death worldwide. Conventional chemotherapy has drawbacks
ranging from limited effectiveness, chemoresistance, and treatment-related side-effects and …