Nanomedicine-based cancer targeting: a new weapon in an old war

PA McCarron, AM Faheem - Nanomedicine, 2010 - Taylor & Francis
There is little doubt that the clinical management of cancer has enjoyed significant
improvements in the past decade, brought about by consolidating the skills and experience …

Nanoparticles Mediated the Diagnosis and Therapy of Glioblastoma: Bypass or Cross the Blood–Brain Barrier

X Song, H Qian, Y Yu - Small, 2023 - Wiley Online Library
Glioblastoma is one of the most aggressive central nervous system malignancies with high
morbidity and mortality. Current clinical approaches, including surgical resection …

A targeted and responsive nanoprodrug delivery system for synergistic glioma chemotherapy

W Zhuo, W Wang, W Zhou, Z Duan, S He, X Zhang, L Yi… - Small, 2024 - Wiley Online Library
Doxorubicin (DOX) is widely used as a chemotherapeutic agent for both hematologic and
solid tumors and is a reasonable candidate for glioma treatment. However, its effectiveness …

Encapsulation of temozolomide in a tumor-targeting nanocomplex enhances anti-cancer efficacy and reduces toxicity in a mouse model of glioblastoma

SS Kim, A Rait, E Kim, J DeMarco, KF Pirollo… - Cancer letters, 2015 - Elsevier
Although temozolomide (TMZ) is the current first-line chemotherapy for glioblastoma
multiforme (GBM), most patients either do not respond or ultimately fail TMZ treatment. Both …

Nanomedicine revisited: next generation therapies for brain cancer

AG Bhargav, SK Mondal, CA Garcia… - Advanced …, 2020 - Wiley Online Library
Brain cancer persists as a difficult‐to‐treat condition. In particular, metastatic brain cancer
and malignant primary brain tumors such as glioblastoma (GBM) are among the most deadly …

Nanotherapy for cancer: targeting and multifunctionality in the future of cancer therapies

A Ediriwickrema, WM Saltzman - ACS biomaterials science & …, 2015 - ACS Publications
Cancer continues to be a prevalent and lethal disease, despite advances in tumor biology
research and chemotherapy development. Major obstacles in cancer treatment arise from …

[HTML][HTML] A recent review on cancer nanomedicine

PM Giri, A Banerjee, B Layek - Cancers, 2023 - mdpi.com
Simple Summary The advancement of nanotechnology over the last three decades has
given new hope to cancer management. The first FDA-approved nanomedicine (DOXIL) was …

Nanotechnology and nanocarrier-based drug delivery as the potential therapeutic strategy for glioblastoma multiforme: An update

JF Hsu, SM Chu, CC Liao, CJ Wang, YS Wang, MY Lai… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) are among the most lethal tumors. The
highly invasive nature and presence of GBM stem cells, as well as the blood brain barrier …

Understanding nanoparticle toxicity to direct a safe-by-design approach in cancer nanomedicine

JA Damasco, S Ravi, JD Perez, DE Hagaman… - Nanomaterials, 2020 - mdpi.com
Nanomedicine is a rapidly growing field that uses nanomaterials for the diagnosis, treatment
and prevention of various diseases, including cancer. Various biocompatible nanoplatforms …

Efficiently targeted therapy of glioblastoma xenograft via multifunctional biomimetic nanodrugs

Z Yao, X Jiang, H Yao, Y Wu, F Zhang… - Biomaterials …, 2022 - spj.science.org
Background Glioblastoma multiforme (GBM) is a fatal malignant primary brain tumor in
adults. The therapeutic efficacy of chemotherapeutic drugs is limited due to the blood-brain …