Several studies have proved that DNA methylation affects regulation of gene expression and
development. Epigenome-wide studies have reported variation in methylation patterns …

Phenotypic characteristics are known to vary substantially among different ethnicities around
the globe. These variations are mediated by number of stochastic events and cannot be …

DNA methylation patterns are important for establishing cell, tissue, and organism
phenotypes, but little is known about their contribution to natural human variation. To …

Background Ethnic differences in human DNA methylation have been shown for a number of
CpG sites, but the genome-wide patterns and extent of these differences are largely …

Variation in DNA methylation is being increasingly associated with health and disease
outcomes. Although DNA methylation is hypothesized to be a mechanism by which both …

The modification of DNA by methylation is an important epigenetic mechanism that affects
the spatial and temporal regulation of gene expression. Methylation patterns have been …

DNA methylation is an essential epigenetic mark whose role in gene regulation and its
dependency on genomic sequence and environment are not fully understood. In this study …

Background Despite the important role DNA methylation plays in transcriptional regulation,
the transgenerational inheritance of DNA methylation is not well understood. The genetic …

DNA methylation is an epigenetic form of gene regulation that is universally important
throughout the life course, especially during in utero and postnatal development. DNA …

Multiple recent studies highlight that genetic variants can have strong impacts on a
significant proportion of the human DNA methylome. Methylation quantitative trait loci, or …