Inter-individual DNA methylation variations were frequently hypothesized to alter individual
susceptibility to Type 2 Diabetes Mellitus (T2DM). Sequence-influenced methylations were …

Background Preterm birth and shorter duration of pregnancy are associated with increased
morbidity in neonatal and later life. As the epigenome is known to have an important role …

Integrating the genotype with epigenetic marks holds the promise of better understanding
the biology that underlies the complex interactions of inherited and environmental …

Although the factors responsible for the recent increase in the prevalence of diabetes
worldwide are not entirely known, the morbidity associated with this disease results in …

Background Preterm birth confers a high risk of adverse long term health outcomes for
survivors, yet the underlying molecular mechanisms are unclear. We hypothesized that …

One plausible mechanism for the environment to alter cancer susceptibility is through DNA
methylation. Alterations in DNA methylation can lead to genomic instability and altered gene …

Background DNA methylation is influenced by both environmental and genetic factors and is
increasingly thought to affect variation in complex traits and diseases. Yet, the extent of …

DNA methylation is an epigenetic mark involved in regulating genome function and is critical
for normal development in mammals. It has been observed that the developmental …

DNA methylation is an important epigenetic modification involved in many biological
processes and diseases. Many studies have mapped DNA methylation changes associated …

BACKGROUND DNA methylation patterns differ among children and adults and play an
unambiguous role in several disease processes, particularly cancers. The origin of these …