Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood
Background Dynamic changes to the epigenome play a critical role in establishing and
maintaining cellular phenotype during differentiation, but little is known about the normal …
maintaining cellular phenotype during differentiation, but little is known about the normal …
Racial differences in gene‐specific DNA methylation levels are present at birth
RM Adkins, J Krushkal, FA Tylavsky… - Birth Defects Research …, 2011 - Wiley Online Library
BACKGROUND DNA methylation patterns differ among children and adults and play an
unambiguous role in several disease processes, particularly cancers. The origin of these …
unambiguous role in several disease processes, particularly cancers. The origin of these …
Worldwide patterns of human epigenetic variation
DNA methylation is an epigenetic modification, influenced by both genetic and
environmental variation, that plays a key role in transcriptional regulation and many …
environmental variation, that plays a key role in transcriptional regulation and many …
Intergenerational genomic DNA methylation patterns in mouse hybrid strains
Background DNA methylation is a contributing factor to both rare and common human
diseases, and plays a major role in development and gene silencing. While the variation of …
diseases, and plays a major role in development and gene silencing. While the variation of …
Genetic and environmental impacts on DNA methylation levels in twins
Epigenetics describes the study of cellular modifications that can modify the expression of
genes without changing the DNA sequence. DNA methylation is one of the most stable and …
genes without changing the DNA sequence. DNA methylation is one of the most stable and …
Methylomic trajectories across human fetal brain development
Epigenetic processes play a key role in orchestrating transcriptional regulation during
development. The importance of DNA methylation in fetal brain development is highlighted …
development. The importance of DNA methylation in fetal brain development is highlighted …
DNA methylation, genotype and gene expression: who is driving and who is along for the ride?
DNA methylation, genotype and gene expression: who is driving and who is along for the ride?
| Genome Biology Skip to main content SpringerLink Account Menu Find a journal Publish with …
| Genome Biology Skip to main content SpringerLink Account Menu Find a journal Publish with …
Cigarette smoking and DNA methylation
KWK Lee, Z Pausova - Frontiers in genetics, 2013 - frontiersin.org
DNA methylation is the most studied epigenetic modification, capable of controlling gene
expression in the contexts of normal traits or diseases. It is highly dynamic during early …
expression in the contexts of normal traits or diseases. It is highly dynamic during early …
The immune factors driving DNA methylation variation in human blood
J Bergstedt, SAK Azzou, K Tsuo, A Jaquaniello… - Nature …, 2022 - nature.com
Epigenetic changes are required for normal development, yet the nature and respective
contribution of factors that drive epigenetic variation in humans remain to be fully …
contribution of factors that drive epigenetic variation in humans remain to be fully …
Genome-wide analysis of DNA methylation dynamics during early human development
H Okae, H Chiba, H Hiura, H Hamada, A Sato… - PLoS …, 2014 - journals.plos.org
DNA methylation is globally reprogrammed during mammalian preimplantation
development, which is critical for normal development. Recent reduced representation …
development, which is critical for normal development. Recent reduced representation …