Background Studies in adult depressed patients have indicated that altered DNA
methylation patterns at genes related to serotonin and HPA axis functioning (eg, SLC6A4 …

Background Epigenetic changes are considered the main mechanisms behind the interplay
of environment and genetic susceptibility in major depressive disorder (MDD). However …

Background Methylation of serotonin-related genes has been proposed as a plausible gene-
by-environment link which may mediate environmental stress, depressive and anxiety …

Dysregulation of stress response systems may mediate the detrimental effects of childhood
trauma (CT) on mental health. FKBP5 regulates glucocorticoid receptor sensitivity and exerts …

Objective DNA methylation has been associated with both early life stress and depression.
This study examined the combined association of DNA methylation at multiple CpG probes …

Mindfulness Based Stress Reduction (MBSR) is an effective non-pharmacologic treatment
for veterans with PTSD. Extensive work has identified epigenetic factors related to PTSD …

As one of the most common psychiatric disorders, depression has been a major public
health problem. Growing evidence suggests that epigenetic modification is essential in …

Background: The aim of the present study was to investigate the association of fMRI blood
oxygen–level dependent (BOLD) reactivity with the level of epigenetic methylation of …

Panic disorder (PD) is one of the most common anxiety disorders and often occurs
comorbidly with major depressive disorder (MDD). Altered methylation of the monoamine …

Importance Depressive disorders arise from a combination of genetic and environmental risk
factors. Epigenetic disruption provides a plausible mechanism through which gene …