[HTML][HTML] A novel CpG island set identifies tissue-specific methylation at developmental gene loci
CpG islands (CGIs) are dense clusters of CpG sequences that punctuate the CpG-deficient
human genome and associate with many gene promoters. As CGIs also differ from bulk …
human genome and associate with many gene promoters. As CGIs also differ from bulk …
ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection
HK Long, NP Blackledge… - Biochemical Society …, 2013 - portlandpress.com
Vertebrate DNA can be chemically modified by methylation of the 5 position of the cytosine
base in the context of CpG dinucleotides. This modification creates a binding site for MBD …
base in the context of CpG dinucleotides. This modification creates a binding site for MBD …
Redefining CpG islands using hidden Markov models
The DNA of most vertebrates is depleted in CpG dinucleotide: a C followed by a G in the 5′
to 3′ direction. CpGs are the target for DNA methylation, a chemical modification of …
to 3′ direction. CpGs are the target for DNA methylation, a chemical modification of …
CpG binding protein is crucial for early embryonic development
DL Carlone, DG Skalnik - Molecular and cellular biology, 2001 - Taylor & Francis
Epigenetic modification of DNA via CpG methylation is essential for the proper regulation of
gene expression during embryonic development. Methylation of CpG motifs results in gene …
gene expression during embryonic development. Methylation of CpG motifs results in gene …
[HTML][HTML] Human genes with CpG island promoters have a distinct transcription-associated chromatin organization
Background More than 50% of human genes initiate transcription from CpG dinucleotide-
rich regions referred to as CpG islands. These genes show differences in their patterns of …
rich regions referred to as CpG islands. These genes show differences in their patterns of …
[HTML][HTML] Transcription initiation patterns indicate divergent strategies for gene regulation at the chromatin level
EA Rach, DR Winter, AM Benjamin, DL Corcoran… - PLoS …, 2011 - journals.plos.org
The application of deep sequencing to map 5′ capped transcripts has confirmed the
existence of at least two distinct promoter classes in metazoans:“focused” promoters with …
existence of at least two distinct promoter classes in metazoans:“focused” promoters with …
[HTML][HTML] KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands
CpG islands (CGIs) are associated with most mammalian gene promoters. A subset of CGIs
act as polycomb response elements (PREs) and are recognized by the polycomb silencing …
act as polycomb response elements (PREs) and are recognized by the polycomb silencing …
Cell type–specific DNA methylation at intragenic CpG islands in the immune system
Human and mouse genomes contain a similar number of CpG islands (CGIs), which are
discrete CpG-rich DNA sequences associated with transcription start sites. In both …
discrete CpG-rich DNA sequences associated with transcription start sites. In both …
[HTML][HTML] CpG islands recruit a histone H3 lysine 36 demethylase
In higher eukaryotes, up to 70% of genes have high levels of nonmethylated
cytosine/guanine base pairs (CpGs) surrounding promoters and gene regulatory units …
cytosine/guanine base pairs (CpGs) surrounding promoters and gene regulatory units …
Determinants of CpG islands: expression in early embryo and isochore structure
L Ponger, L Duret, D Mouchiroud - Genome research, 2001 - genome.cshlp.org
In an attempt to understand the origin of CpG islands (CGIs) in mammalian genomes, we
have studied their location and structure according to the expression pattern of genes and to …
have studied their location and structure according to the expression pattern of genes and to …