Aims Angiotensin-converting enzyme (ACE) inhibitors improve left ventricular (LV)
remodelling and outcome in heart failure and hypertensive heart disease. They may be …

Background Despite the importance of the renin-angiotensin (Ang) system in abdominal
aortic aneurysm (AAA) pathogenesis, strategies targeting this system to prevent clinical …

FIVE years ago Atkinson and Robertson surveyed the use of captopril, the first orally active
inhibitor of the renin-angiotensin system, in the treatment of clinical hypertension and …

Pneumonia is a major direct cause of death in the elderly. Although aspiration based on a
reduced cough reflex is one of the causes of pneumonia in the elderly, there are few studies …

The angiotensin converting enzyme (ACE) inhibitors are a group of effective drugs with a
unique mechanism of action. These drugs have proven to be useful for hypertension and …

Objective This review describes ongoing efforts to develop a medical therapy to limit
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …

ACE inhibitors effectively reduce systemic vascular resistance in patients with hypertension,
heart failure or chronic renal disease. This antihypertensive efficacy probably accounts for …

Proven cardiovascular benefit from angiotensin-converting enzyme (ACE) inhibition is a
cornerstone of evidence-based medicine. The first study to show dramatic benefits from ACE …

Background Calcium accumulation in the aortic valve is a hallmark of aortic sclerosis and
aortic stenosis. Because lipoproteins, angiotensin-converting enzyme, and angiotensin II …

This paper reports the rationale for the cardiovascular protective effects of ACE inhibitors
(ACEI) and reviews the overall results of recent randomized clinical trials. ACEI improve the …