[引用][C] DNA methylation and gene activity

W Doerfler - Annual review of biochemistry, 1983 - annualreviews.org
DNA methylation and its functional significance, particularly in eukaryotic systems, have
become very active areas of research. Although the biochem istry of DNA methylation has …

Dna Methylation in Eukaryote

RLP Adams, RH Burdon… - Critical Reviews in …, 1982 - Taylor & Francis
In addition to the four bases incorporated into DNA during semiconservative replication
there is a variable number of other bases present in DNA in small amounts. These arise by …

DNA methylation and its possible biological roles

A Razin, J Friedman - Progress in nucleic acid research and molecular …, 1981 - Elsevier
Publisher Summary The chapter discusses on the DNA methylation and its possible
biological roles. The pattern of DNA methylation is species-specific. In the DNA of some …

DNA methylase: purification from ascites cells and the effect of various DNA substrates on its activity.

JF Turnbull, RLP Adams - Nucleic Acids Research, 1976 - academic.oup.com
DNA methylase has been purified 405-fold from Krebs II ascites cells. The purified enzyme is
homogeneous on SDS-poly acrylamide gel electrophoresis (molecular weight about 80,000) …

DNA methylation. The effect of minor bases on DNA-protein interactions

RLP Adams - Biochemical journal, 1990 - portlandpress.com
DNA methylation is found almost ubiquitously in nature and the methyltransferases show
evidence of a common evolutionary origin. It will be a fascinating study in protein evolution …

Methylation of DNA in prokaryotes

M Noyer-Weidner, TA Trautner - DNA methylation: molecular biology and …, 1993 - Springer
A much wider variety of biological functions of postreplicative DNA methylation is observed
in prokaryotes than in eukaryotes. In eukaryotes DNA methylation is primarily a means of the …

Restriction enzyme digestion of hemimethylated DNA

Y Gruenbaum, H Cedar, A Razin - Nucleic acids research, 1981 - academic.oup.com
Hemimethylated duplex DNA of the bacteriophage ØX 174 was synthesized using primed
repair synthesis in vitro with E. coli DNA polymerase I followed by ligation to produce the …

[图书][B] DNA methylation: molecular biology and biological significance

J Jost, H Saluz - 2013 - books.google.com
The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see
first chapter). Recognition of its possible physiologi cal role in eucaryotes was first …

Mouse DNA methylase: methylation of native DNA

RLP Adams, EL McKay, LM Craig… - Biochimica et Biophysica …, 1979 - Elsevier
An improved method of purification of DNA methylase from Krebs II ascites cells is reported.
The enzyme sediments at 8.3 S on glycerol-gradients and a major band on SDS …

DNA methylation—a regulatory signal in eukaryotic gene expression

W Doerfler - Journal of General Virology, 1981 - microbiologyresearch.org
There are at least two systems in which inhibitory effects of DNA modification on DNA-
protein interactions have been unambiguously demonstrated.(i) At sequences specifically …