Our knowledge about the neuropharmacology of addiction is increasing and is leading to
more informed development of pharmacotherapy. Although the dopaminergic mesolimbic …

The final common pathway of addiction (the dopamine hypothesis of reward) has recently
been evolving, with the mesocorticolimbic dopaminergic system now seen as key to natural …

The last decade brought a considerable progress in pharmacotherapy of addiction. Basing
on recently gained knowledge of mechanisms of development of addiction and the …

This review gives an overview of what we see as the key issues in the human pharmacology
of drugs of addiction. We review evidence of efficacy and mechanisms by which treatments …

Substance addiction is a chronic, relapsing disorder characterized by a compulsion to take a
substance despite potential consequences. Addiction, second edition offers a clear and …

Substance use disorders represent a serious public health and social issue worldwide.
Recent advances in our understanding of the neurobiological basis of the addictive …

Until recently, much of our knowledge of the neuropharmacology of addiction was derived
from animal studies, but we are now able to study the human brain directly and there is a …

It needs no explanation that addiction is an extremely serious problem, considering its
impact on both health and society. Unsurprisingly, addiction is a major focus of …

Drug addiction presents as a chronic relapsing disorder characterized by persistent drug‐
seeking and drug‐taking behaviours. Given the significant detrimental effects of this disease …

Drug abuse represents a considerable burden of disease and has enormous economic
impacts on societies. Over the years, few medications have been developed for clinical use …