Many differentially methylated genes have been identified in prostate cancer (PCa),
primarily using candidate gene-based assays. Recently, several global DNA methylation …

Background Aberrant DNA methylation may promote prostate carcinogenesis. We
investigated epigenome‐wide DNA methylation profiles in prostate cancer (PCa) compared …

Altered genome methylation is a hallmark of human malignancies. In this study, high-
throughput analyses of concordant gene methylation and expression events were performed …

Background: Prostate cancer (PCa) harbors a myriad of genomic and epigenetic defects.
Cytosine methylation of CpG-rich promoter DNA is an important mechanism of epigenetic …

Prostate cancer (PCa) is the most prevalent cancer, a significant contributor to morbidity and
a leading cause of cancer-related death in men in Western industrialized countries. In …

Abstract Background Prostate cancer (PCa) has the highest incidence rates of cancers in
men in western countries. Unlike several other types of cancer, PCa has few genetic drivers …

Promoter hypermethylation is associated with the loss of expression of tumor-suppressor
genes in cancer. Currently, several genome-wide technologies are available and have been …

Abstract Background Prostate cancer (PCa) remains the second leading cause of deaths
due to cancer in the United States in men. The aim of this study was to perform an integrative …

Increasing evidence suggests that aberrant DNA methylation changes may contribute to
prostate cancer (PCa) ethnic disparity. To comprehensively identify DNA methylation …

Candidate gene-based studies have identified a handful of aberrant CpG DNA methylation
events in prostate cancer. However, DNA methylation profiles have not been compared on a …