Recent research highlights the role of CpG methylation in genomic imprinting, histone and
chromatin modification, transcriptional regulation, and 'gene silencing'in cancer …

Cytosine methylation is an epigenetic mechanism in eukaryotes that is often associated with
stable transcriptional silencing, such as in X-chromosome inactivation and genomic …

The character of a cell is defined by its constituent proteins, which are the result of specific
patterns of gene expression. Crucial determinants of gene expression patterns are DNA …

Proper establishment and faithful maintenance of epigenetic information is crucial for the
correct development of complex organisms. For mammals, it is now accepted that DNA …

We present a model for the kinetics of methylation and demethylation of eukaryotic DNA; the
model incorporates values for de novo methylation and the error rate of maintenance …

DNA methylation is an essential epigenetic mark whose role in gene regulation and its
dependency on genomic sequence and environment are not fully understood. In this study …

It has been nearly 40 y since it was suggested that genomic methylation patterns could be
transmitted via maintenance methylation during S phase and might play a role in the …

DNA methylation is a key epigenetic process which has been intimately associated with
gene regulation. In recent years growing evidence has associated DNA methylation status …

From a fertilised egg to a mature organism, cells divide and accumulate epigenetic
information, which is faithfully passed on to daughter cells. DNA methylation consolidates …

Epigenetics is the study of all mechanisms that regulate gene transcription and genome
stability that are maintained throughout the cell division, but do not include the DNA …